Differential regional N -acetylaspartate deficits in postmortem brain in schizophrenia, bipolar disorder and major depressive disorder

Abstract There is substantial evidence for the involvement of the hippocampus and subcortical regions in the neuropathology of schizophrenia. Deficits of N -acetylaspartate (NAA) have been found in schizophrenia and bipolar disorder which may reflect neuronal loss and/or dysfunction. N -acetylaspart...

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Veröffentlicht in:	Journal of psychiatric research 2011-01, Vol.45 (1), p.54-59
Hauptverfasser:	Reynolds, Lindsay M, Reynolds, Gavin P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Aspartic Acid - analogs & derivatives Aspartic Acid - metabolism Biological and medical sciences Bipolar affective disorder Bipolar disorder Bipolar Disorder - pathology Bipolar disorders Brain - metabolism Brain - pathology Depression Depressive Disorder, Major - pathology Depressive personality disorders Dipeptides - metabolism Female Frozen brain sections Humans Indexing in process Major depressive disorder Male Medical sciences Middle Aged Mood disorders N-acetylaspartate N-acetylaspartylglutamate Nervous system Neuropathology Postmortems Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Schizophrenia Schizophrenia - pathology
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