Trichinellosis in Children and Adults: A 10-Year Comparative Study in Western Romania
INTRODUCTION:This study aims to evaluate and compare the epidemiologic, laboratory, clinical, and therapeutic aspects of trichinellosis in child and adult populations residing in Western Romania. PATIENTS AND METHODS:We have retrospectively investigated the medical records of patients with trichinel...
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| Veröffentlicht in: | The Pediatric infectious disease journal 2011-05, Vol.30 (5), p.392-395 |
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| container_title | The Pediatric infectious disease journal |
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| creator | Neghina, Raul Neghina, Adriana Maria Marincu, Iosif Iacobiciu, Ioan |
| description | INTRODUCTION:This study aims to evaluate and compare the epidemiologic, laboratory, clinical, and therapeutic aspects of trichinellosis in child and adult populations residing in Western Romania.
PATIENTS AND METHODS:We have retrospectively investigated the medical records of patients with trichinellosis hospitalized between 1996 and 2005 in 5 infectious diseases hospitals located in 4 Western Romanian counties.
RESULTS:Trichinellosis was diagnosed in 1344 patients, of whom 348 were children (26%) and 996 were adults (74%). The annual average incidence was 8.4 cases per 100,000 in children and 7.7 cases per 100,000 in adults. The mean ages for the children and adults were 11 ± 4.4 years and 38.1 ± 14.2 years, respectively. Myalgias and complications of trichinellosis were detected less frequently in children who also had lower eosinophil counts, leukocyte counts, and erythrocyte sedimentation rates compared with those for adults. Albendazole and mebendazole had comparable efficacies in adult patients; however, albendazole proved to be a better choice than mebendazole for the treatment of children.
CONCLUSIONS:Trichinellosis occurs commonly among inhabitants of Western Romania. Although the general trend of decline in the incidence of trichinellosis cases cannot be used as a statistical predictor of future improvement, it provides encouragement and demonstrates the need for the implementation of correct public health and educational measures to fully prevent and eradicate trichinellosis in Western Romania. |
| doi_str_mv | 10.1097/INF.0b013e31820415ad |
| format | Article |
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PATIENTS AND METHODS:We have retrospectively investigated the medical records of patients with trichinellosis hospitalized between 1996 and 2005 in 5 infectious diseases hospitals located in 4 Western Romanian counties.
RESULTS:Trichinellosis was diagnosed in 1344 patients, of whom 348 were children (26%) and 996 were adults (74%). The annual average incidence was 8.4 cases per 100,000 in children and 7.7 cases per 100,000 in adults. The mean ages for the children and adults were 11 ± 4.4 years and 38.1 ± 14.2 years, respectively. Myalgias and complications of trichinellosis were detected less frequently in children who also had lower eosinophil counts, leukocyte counts, and erythrocyte sedimentation rates compared with those for adults. Albendazole and mebendazole had comparable efficacies in adult patients; however, albendazole proved to be a better choice than mebendazole for the treatment of children.
CONCLUSIONS:Trichinellosis occurs commonly among inhabitants of Western Romania. Although the general trend of decline in the incidence of trichinellosis cases cannot be used as a statistical predictor of future improvement, it provides encouragement and demonstrates the need for the implementation of correct public health and educational measures to fully prevent and eradicate trichinellosis in Western Romania.</description><identifier>ISSN: 0891-3668</identifier><identifier>EISSN: 1532-0987</identifier><identifier>DOI: 10.1097/INF.0b013e31820415ad</identifier><identifier>PMID: 21099443</identifier><identifier>CODEN: PIDJEV</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins, Inc</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Albendazole - pharmacology ; Albendazole - therapeutic use ; Anthelmintics - pharmacology ; Anthelmintics - therapeutic use ; Biological and medical sciences ; Child ; Child, Preschool ; Diseases caused by nematodes ; Female ; General aspects ; Helminthic diseases ; Humans ; Incidence ; Infant ; Infectious diseases ; Male ; Mebendazole - pharmacology ; Mebendazole - therapeutic use ; Medical sciences ; Middle Aged ; Parasitic diseases ; Retrospective Studies ; Romania - epidemiology ; Trichinellosis - diagnosis ; Trichinellosis - epidemiology ; Trichinellosis - pathology ; Trichinellosis - therapy ; Trichinosis ; Young Adult</subject><ispartof>The Pediatric infectious disease journal, 2011-05, Vol.30 (5), p.392-395</ispartof><rights>2011 Lippincott Williams & Wilkins, Inc.</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c334d-12232bbcd9df217d8638786ac30ca86727ed1642e288b31ff58687f64f7e21313</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24153742$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21099443$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Neghina, Raul</creatorcontrib><creatorcontrib>Neghina, Adriana Maria</creatorcontrib><creatorcontrib>Marincu, Iosif</creatorcontrib><creatorcontrib>Iacobiciu, Ioan</creatorcontrib><title>Trichinellosis in Children and Adults: A 10-Year Comparative Study in Western Romania</title><title>The Pediatric infectious disease journal</title><addtitle>Pediatr Infect Dis J</addtitle><description>INTRODUCTION:This study aims to evaluate and compare the epidemiologic, laboratory, clinical, and therapeutic aspects of trichinellosis in child and adult populations residing in Western Romania.
PATIENTS AND METHODS:We have retrospectively investigated the medical records of patients with trichinellosis hospitalized between 1996 and 2005 in 5 infectious diseases hospitals located in 4 Western Romanian counties.
RESULTS:Trichinellosis was diagnosed in 1344 patients, of whom 348 were children (26%) and 996 were adults (74%). The annual average incidence was 8.4 cases per 100,000 in children and 7.7 cases per 100,000 in adults. The mean ages for the children and adults were 11 ± 4.4 years and 38.1 ± 14.2 years, respectively. Myalgias and complications of trichinellosis were detected less frequently in children who also had lower eosinophil counts, leukocyte counts, and erythrocyte sedimentation rates compared with those for adults. Albendazole and mebendazole had comparable efficacies in adult patients; however, albendazole proved to be a better choice than mebendazole for the treatment of children.
CONCLUSIONS:Trichinellosis occurs commonly among inhabitants of Western Romania. Although the general trend of decline in the incidence of trichinellosis cases cannot be used as a statistical predictor of future improvement, it provides encouragement and demonstrates the need for the implementation of correct public health and educational measures to fully prevent and eradicate trichinellosis in Western Romania.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Albendazole - pharmacology</subject><subject>Albendazole - therapeutic use</subject><subject>Anthelmintics - pharmacology</subject><subject>Anthelmintics - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Diseases caused by nematodes</subject><subject>Female</subject><subject>General aspects</subject><subject>Helminthic diseases</subject><subject>Humans</subject><subject>Incidence</subject><subject>Infant</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Mebendazole - pharmacology</subject><subject>Mebendazole - therapeutic use</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Parasitic diseases</subject><subject>Retrospective Studies</subject><subject>Romania - epidemiology</subject><subject>Trichinellosis - diagnosis</subject><subject>Trichinellosis - epidemiology</subject><subject>Trichinellosis - pathology</subject><subject>Trichinellosis - therapy</subject><subject>Trichinosis</subject><subject>Young Adult</subject><issn>0891-3668</issn><issn>1532-0987</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtKxDAUhoMoOl7eQCQbcdUxt0lSd0NxdEAUvCCuSpqkTDRtx6RVfHsjMyq4cHU23_-fcz4ADjEaY5SL0_n1bIwqhKmlWBLE8ESZDTDCE0oylEuxCUZI5jijnMsdsBvjM0KIMoy2wQ5JDTljdAQe7oPTC9da77voInQtLBbOm2BbqFoDp2bwfTyDU4hR9mRVgEXXLFVQvXuz8K4fzMdX5tHG3oYW3naNap3aB1u18tEerOceeJid3xeX2dXNxbyYXmWaUmYyTAglVaVNbmqChZGcSiG50hRpJbkgwhrMGbFEyoriup5ILkXNWS0swRTTPXCy6l2G7nVIN5SNizr9olrbDbGUnBCeo5wnkq1IHboYg63LZXCNCh8lRuWXzzL5LP_6TLGj9YKhaqz5CX0LTMDxGlBRK18H1WoXf7lUQwUjiZMr7r3zyVR88cO7DeXCKt8v_r_hE4jzju4</recordid><startdate>201105</startdate><enddate>201105</enddate><creator>Neghina, Raul</creator><creator>Neghina, Adriana Maria</creator><creator>Marincu, Iosif</creator><creator>Iacobiciu, Ioan</creator><general>Lippincott Williams & Wilkins, Inc</general><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201105</creationdate><title>Trichinellosis in Children and Adults: A 10-Year Comparative Study in Western Romania</title><author>Neghina, Raul ; Neghina, Adriana Maria ; Marincu, Iosif ; Iacobiciu, Ioan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c334d-12232bbcd9df217d8638786ac30ca86727ed1642e288b31ff58687f64f7e21313</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Albendazole - pharmacology</topic><topic>Albendazole - therapeutic use</topic><topic>Anthelmintics - pharmacology</topic><topic>Anthelmintics - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Diseases caused by nematodes</topic><topic>Female</topic><topic>General aspects</topic><topic>Helminthic diseases</topic><topic>Humans</topic><topic>Incidence</topic><topic>Infant</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Mebendazole - pharmacology</topic><topic>Mebendazole - therapeutic use</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Parasitic diseases</topic><topic>Retrospective Studies</topic><topic>Romania - epidemiology</topic><topic>Trichinellosis - diagnosis</topic><topic>Trichinellosis - epidemiology</topic><topic>Trichinellosis - pathology</topic><topic>Trichinellosis - therapy</topic><topic>Trichinosis</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Neghina, Raul</creatorcontrib><creatorcontrib>Neghina, Adriana Maria</creatorcontrib><creatorcontrib>Marincu, Iosif</creatorcontrib><creatorcontrib>Iacobiciu, Ioan</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Pediatric infectious disease journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Neghina, Raul</au><au>Neghina, Adriana Maria</au><au>Marincu, Iosif</au><au>Iacobiciu, Ioan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Trichinellosis in Children and Adults: A 10-Year Comparative Study in Western Romania</atitle><jtitle>The Pediatric infectious disease journal</jtitle><addtitle>Pediatr Infect Dis J</addtitle><date>2011-05</date><risdate>2011</risdate><volume>30</volume><issue>5</issue><spage>392</spage><epage>395</epage><pages>392-395</pages><issn>0891-3668</issn><eissn>1532-0987</eissn><coden>PIDJEV</coden><abstract>INTRODUCTION:This study aims to evaluate and compare the epidemiologic, laboratory, clinical, and therapeutic aspects of trichinellosis in child and adult populations residing in Western Romania.
PATIENTS AND METHODS:We have retrospectively investigated the medical records of patients with trichinellosis hospitalized between 1996 and 2005 in 5 infectious diseases hospitals located in 4 Western Romanian counties.
RESULTS:Trichinellosis was diagnosed in 1344 patients, of whom 348 were children (26%) and 996 were adults (74%). The annual average incidence was 8.4 cases per 100,000 in children and 7.7 cases per 100,000 in adults. The mean ages for the children and adults were 11 ± 4.4 years and 38.1 ± 14.2 years, respectively. Myalgias and complications of trichinellosis were detected less frequently in children who also had lower eosinophil counts, leukocyte counts, and erythrocyte sedimentation rates compared with those for adults. Albendazole and mebendazole had comparable efficacies in adult patients; however, albendazole proved to be a better choice than mebendazole for the treatment of children.
CONCLUSIONS:Trichinellosis occurs commonly among inhabitants of Western Romania. Although the general trend of decline in the incidence of trichinellosis cases cannot be used as a statistical predictor of future improvement, it provides encouragement and demonstrates the need for the implementation of correct public health and educational measures to fully prevent and eradicate trichinellosis in Western Romania.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>21099443</pmid><doi>10.1097/INF.0b013e31820415ad</doi><tpages>4</tpages></addata></record> |
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| subjects | Adolescent Adult Aged Aged, 80 and over Albendazole - pharmacology Albendazole - therapeutic use Anthelmintics - pharmacology Anthelmintics - therapeutic use Biological and medical sciences Child Child, Preschool Diseases caused by nematodes Female General aspects Helminthic diseases Humans Incidence Infant Infectious diseases Male Mebendazole - pharmacology Mebendazole - therapeutic use Medical sciences Middle Aged Parasitic diseases Retrospective Studies Romania - epidemiology Trichinellosis - diagnosis Trichinellosis - epidemiology Trichinellosis - pathology Trichinellosis - therapy Trichinosis Young Adult |
| title | Trichinellosis in Children and Adults: A 10-Year Comparative Study in Western Romania |
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