A vaccine prepared from a non-pathogenic H5N1 influenza virus strain from the influenza virus library conferred protective immunity to chickens against the challenge with antigenically drifted highly pathogenic avian influenza virus

Inactivated influenza virus vaccine prepared from a non-pathogenic influenza virus strain A/duck/Hokkaido/Vac-1/2004 (H5N1) from the virus library conferred protective immunity to chickens against the challenge of antigenically drifted highly pathogenic avian influenza virus (HPAIV), A/whooper swan/...

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Veröffentlicht in:The Japanese journal of veterinary research 2011-02, Vol.59 (1), p.23-29
Hauptverfasser: Samad, Rozanah Asmah Abdul, Nomura, Naoki, Tsuda, Yoshimi, Manzoor, Rashid, Kajihara, Masahiro, Tomabechi, Daisuke, Sasaki, Takashi, Kokumai, Norihide, Ohgitani, Toshiaki, Okamatsu, Masatoshi, Takada, Ayato, Sakoda, Yoshihiro, Kida, Hiroshi
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container_issue 1
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container_title The Japanese journal of veterinary research
container_volume 59
creator Samad, Rozanah Asmah Abdul
Nomura, Naoki
Tsuda, Yoshimi
Manzoor, Rashid
Kajihara, Masahiro
Tomabechi, Daisuke
Sasaki, Takashi
Kokumai, Norihide
Ohgitani, Toshiaki
Okamatsu, Masatoshi
Takada, Ayato
Sakoda, Yoshihiro
Kida, Hiroshi
description Inactivated influenza virus vaccine prepared from a non-pathogenic influenza virus strain A/duck/Hokkaido/Vac-1/2004 (H5N1) from the virus library conferred protective immunity to chickens against the challenge of antigenically drifted highly pathogenic avian influenza virus (HPAIV), A/whooper swan/Hokkaido/1/2008 (H5N1). The efficacy of the vaccine was comparable to that prepared from genetically modified HPAIV strain deltaRRRRK rg-A/ whooper swan/Mongolia/3/2005 (H5N1), which is more antigenically related to the challenge virus strain, in chickens.
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subjects Animals
Anseriformes - immunology
Anseriformes - virology
Antibodies, Viral - analysis
Antibodies, Viral - biosynthesis
Antibody Specificity
Chickens
Cross Reactions
Disease Outbreaks - prevention & control
DNA, Viral - genetics
Ducks - immunology
Ducks - virology
Influenza A Virus, H5N1 Subtype - immunology
Influenza A Virus, H5N1 Subtype - physiology
Influenza in Birds - genetics
Influenza in Birds - immunology
Influenza in Birds - prevention & control
Influenza Vaccines - administration & dosage
Influenza Vaccines - genetics
Influenza Vaccines - immunology
Mongolia
Reassortant Viruses - growth & development
Reassortant Viruses - immunology
title A vaccine prepared from a non-pathogenic H5N1 influenza virus strain from the influenza virus library conferred protective immunity to chickens against the challenge with antigenically drifted highly pathogenic avian influenza virus
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