C‐Src is required for complex formation between the hepatitis C virus–encoded proteins NS5A and NS5B: A prerequisite for replication

Hepatitis C virus (HCV) is a leading cause of chronic liver disease worldwide and establishes a persistent infection in more than 60% of infected individuals. This high frequency of persistent infection indicates that HCV has evolved efficient strategies to interfere with the adaptive and innate imm...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2011-04, Vol.53 (4), p.1127-1136
Hauptverfasser:	Pfannkuche, Andreas, Büther, Katrin, Karthe, Juliane, Poenisch, Marion, Bartenschlager, Ralf, Trilling, Mirko, Hengel, Hartmut, Willbold, Dieter, Häussinger, Dieter, Bode, Johannes Georg
Format:	Artikel
Sprache:	eng
Schlagworte:	Benzoquinones - pharmacology Biological and medical sciences Cell Line, Tumor Gastroenterology. Liver. Pancreas. Abdomen Hepacivirus - genetics Hepacivirus - physiology Hepatitis Hepatitis C Hepatitis C virus Hepatology HIV Human immunodeficiency virus Humans Lactams, Macrocyclic - pharmacology Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Proteins Rifabutin - analogs & derivatives RNA-Dependent RNA Polymerase - genetics src Homology Domains - genetics src-Family Kinases - physiology Viral Nonstructural Proteins Virus Replication
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