Structural and Functional Roles of Daxx SIM Phosphorylation in SUMO Paralog-Selective Binding and Apoptosis Modulation

Small ubiquitin-like modifier (SUMO) conjugation and interaction are increasingly associated with various cellular processes. However, little is known about the cellular signaling mechanisms that regulate proteins for distinct SUMO paralog conjugation and interactions. Using the transcriptional core...

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Veröffentlicht in:	Molecular cell 2011-04, Vol.42 (1), p.62-74
Hauptverfasser:	Chang, Che-Chang, Naik, Mandar T., Huang, Yen-Sung, Jeng, Jen-Chong, Liao, Pei-Hsin, Kuo, Hong-Yi, Ho, Chun-Chen, Hsieh, Yung-Lin, Lin, Chiou-Hong, Huang, Nai-Jia, Naik, Nandita M., Kung, Camy C.-H., Lin, Shu-Yu, Chen, Ruey-Hwa, Chang, Kun-Sang, Huang, Tai-Huang, Shih, Hsiu-Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - chemistry Adaptor Proteins, Signal Transducing - genetics Adaptor Proteins, Signal Transducing - metabolism Amino Acid Sequence Animals apoptosis Apoptosis - genetics Apoptosis - physiology binding capacity Carrier Proteins - chemistry Carrier Proteins - genetics Carrier Proteins - metabolism Casein Kinase II - metabolism cell communication Cell Line genes HeLa Cells Humans Intracellular Signaling Peptides and Proteins - chemistry Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Mice Models, Molecular nuclear magnetic resonance spectroscopy Nuclear Proteins - chemistry Nuclear Proteins - genetics Nuclear Proteins - metabolism Phosphorylation Protein Binding Protein Interaction Domains and Motifs proteins Small Ubiquitin-Related Modifier Proteins - metabolism Stress, Physiological SUMO-1 Protein - metabolism transcription (genetics)
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