Duality of effect of La³⁺ on mitochondrial permeability transition pore depending on the concentration

In order to explore the role of mitochondria in proliferation promotion and/or apoptosis induction of lanthanum, the mutual influences between La³⁺ and Ca²⁺ on mitochondrial permeability transition pore (PTP) opening were investigated with isolated mitochondria from rat liver. The experimental resul...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biometals 2009-12, Vol.22 (6), p.917-926
Hauptverfasser:	Dong, Shuai, Zhao, Yuebin, Liu, Huixue, Yang, Xiaoda, Wang, Kui
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Apoptosis - drug effects Biochemistry Biomedical and Life Sciences Calcium - metabolism Calcium - pharmacology Calcium Channels - metabolism Cell Biology Cell Proliferation - drug effects Cellular biology Cyclosporine - pharmacology Cytochromes c - analysis Dose-Response Relationship, Drug Eukaryotes Ions Lanthanum Lanthanum - metabolism Lanthanum - pharmacology Life Sciences Medicine/Public Health Membrane Potential, Mitochondrial - drug effects Microbiology Mitochondria, Liver - drug effects Mitochondria, Liver - metabolism Mitochondrial Membrane Transport Proteins - antagonists & inhibitors Mitochondrial Membrane Transport Proteins - metabolism Mitochondrial Swelling - drug effects Permeability Permeability - drug effects Pharmacology/Toxicology Plant Physiology Rats Rats, Inbred Strains Reactive Oxygen Species - metabolism Ruthenium Red - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!