Ten-year Experiences on Initial Genetic Examination in Childhood Acute Lymphoblastic Leukaemia in Hungary (1993–2002). Technical Approaches and Clinical Implementation

A nationwide study was started in 1993 to provide genetic diagnosis for all newly diagnosed childhood ALL cases in Hungary using cytogenetic examination, DNA-index determination, FISH (aneuploidy, ABL/BCR, TEL/AML1) and molecular genetic tests (ABL/BCR, MLL/AF4, TEL/AML1). Aim of the study was to as...

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Veröffentlicht in:	Pathology oncology research 2011-03, Vol.17 (1), p.81-90
Hauptverfasser:	Olah, Eva, Balogh, Erzsebet, Pajor, Laszlo, Jakab, Zsuzsanna
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Algorithms Biomedical and Life Sciences Biomedicine Cancer Research Cell Separation Child Child, Preschool Cytogenetic Analysis - standards Female Flow Cytometry Genetic Testing - methods Genetic Testing - standards Humans Hungary Immunology In Situ Hybridization, Fluorescence Infant Infant, Newborn Kaplan-Meier Estimate Male Oncology Pathology Precursor Cell Lymphoblastic Leukemia-Lymphoma - diagnosis Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality Predictive Value of Tests Prognosis Reverse Transcriptase Polymerase Chain Reaction Time Factors
Online-Zugang:	Volltext
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