Association of UGT2B7 and ABCB1 genotypes with morphine-induced adverse drug reactions in Japanese patients with cancer

Purpose To investigate the effects of genetic polymorphisms on morphine-induced adverse events in cancer patients. Methods We examined the relation of morphine-related adverse events to polymorphisms in UDP-glucuronosyltransferase (UGT) 2B7, ATP-binding cassette, sub-family B, number 1 (ABCB1), and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer chemotherapy and pharmacology 2010, Vol.65 (2), p.251-258
Hauptverfasser:	Fujita, Ken-ichi, Ando, Yuichi, Yamamoto, Wataru, Miya, Toshimichi, Endo, Hisashi, Sunakawa, Yu, Araki, Kazuhiro, Kodama, Keiji, Nagashima, Fumio, Ichikawa, Wataru, Narabayashi, Masaru, Akiyama, Yuko, Kawara, Kaori, Shiomi, Mari, Ogata, Hiroyasu, Iwasa, Hiroyasu, Okazaki, Yasushi, Hirose, Takashi, Sasaki, Yasutsuna
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Analgesics, Opioid - adverse effects Analgesics, Opioid - pharmacokinetics Antineoplastic agents Asian Continental Ancestry Group ATP Binding Cassette Transporter, Sub-Family B ATP-Binding Cassette, Sub-Family B, Member 1 - genetics Biological and medical sciences Cancer Research Delayed-Action Preparations Female Genetic Association Studies Genotype Glucuronosyltransferase - genetics Humans Japan Male Medical sciences Medicine Medicine & Public Health Middle Aged Morphine - adverse effects Morphine - pharmacokinetics Neoplasms - physiopathology Oncology Original Article Pain - drug therapy Pharmacology. Drug treatments Pharmacology/Toxicology Polymorphism, Genetic Receptors, Opioid, mu - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!