Linkage and association of proinflammatory cytokines genes IL-6, IFNG and TNF with multiple sclerosis

Proinflammatory cytokines interleukin-6 (IL-6), interferon-γ (IFNg) and tumor necrosis factor (TNF) play an important role in the pathogenesis of multiple sclerosis. Based on the published data concerning the effects of the SNPs G(−308)A of TNF, A(+874)T of IFNG, and G(−174)C of IL-6 on the producti...

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Veröffentlicht in:	Molecular biology (New York) 2010-10, Vol.44 (5), p.728-733
Hauptverfasser:	Makarycheva, O. Yu, Tsareva, E. Yu, Sudomoina, M. A, Kulakova, O. G, Bykova, O. V, Gol'tsova, N. V, Kuzenkova, L. M, Boiko, A. N, Favorova, O. O
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Biosynthesis Children Cytokines Families & family life Genomics and Transcriptomics Human Genetics Life Sciences Multiple sclerosis Population genetics
Online-Zugang:	Volltext
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