Interplay of measles virus with early induced cytokines reveals different wild type phenotypes

Differential effects of measles virus (MV) on the innate immune response may influence virus spread and severity of disease. Using a representative panel of 22 MV strains including 14 different genotypes, we found that wild-type (wt) differ considerably in their sensitivity to type I interferon (IFN...

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Veröffentlicht in:	Virus research 2011, Vol.155 (1), p.195-202
Hauptverfasser:	Kessler, Julia R., Kremer, Jacques R., Muller, Claude P.
Format:	Artikel
Sprache:	eng
Schlagworte:	5′ copy-back diRNA amino acids Animals Cell Line Cercopithecus aethiops Cytokine Cytokines - immunology defense mechanisms disease severity DNA Mutational Analysis genes Genotype Humans Immune Evasion in vitro studies innate immunity Interferon interferon-alpha Measles Measles virus Measles virus - immunology Molecular Sequence Data mutation necrosis patients Phenotype RNA sequence analysis Sequence Analysis, DNA tempering tumor necrosis factor-alpha vaccines virulence Virus Replication viruses
Online-Zugang:	Volltext
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