Roles of β-adrenergic receptors in Alzheimer's disease: Implications for novel therapeutics

Abstract Alzheimer's disease (AD), the most common cause of age-related dementia, is a progressive neurodegenerative disorder with an enormous unmet medical need. In recent years, several unexpected longitudinal and cross-sectional epidemiological studies reveal that beta-blockers treatment red...

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Veröffentlicht in:	Brain research bulletin 2011-02, Vol.84 (2), p.111-117
Hauptverfasser:	Yu, Jin-Tai, Wang, Nai-Dong, Ma, Teng, Jiang, Hong, Guan, Jun, Tan, Lan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - therapeutic use Alzheimer Disease - drug therapy Alzheimer Disease - pathology Alzheimer Disease - physiopathology Alzheimer's disease Amyloid beta Clinical Trials as Topic Cognition - drug effects Homeostasis Humans Hypertension - drug therapy Inflammation Neurology Norepinephrine - metabolism Receptors, Adrenergic, beta - metabolism Treatment β2-Adrenergic receptor
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