Survey of ocular irritation predictive capacity using Chorioallantoic Membrane Vascular Assay (CAMVA) and Bovine Corneal Opacity and Permeability (BCOP) test historical data for 319 personal care products over fourteen years

The Chorioallantoic Membrane Vascular Assay (CAMVA) and Bovine Corneal Opacity and Permeability (BCOP) test are widely used to predict ocular irritation potential for consumer-use products. These in vitro assays do not require live animals, produce reliable predictive data for defined applicability...

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Veröffentlicht in:	Toxicology in vitro 2011-03, Vol.25 (2), p.563-572
Hauptverfasser:	Donahue, D.A., Kaufman, L.E., Avalos, J., Simion, F.A., Cerven, D.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bovine Corneal Opacity and Permeability (BCOP) Cattle Chemistry, Pharmaceutical Chorioallantoic membrane Chorioallantoic Membrane - blood supply Chorioallantoic Membrane - drug effects Chorioallantoic Membrane Vascular Assay (CAMVA) Corneal Opacity - chemically induced Cosmetics Cosmetics - toxicity Ethanol - toxicity Eye - drug effects Eye irritation Irritants - toxicity Ocular irritation Personal care products Rabbits Surface-Active Agents - toxicity
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