Soluble CD93 induces differentiation of monocytes and enhances TLR responses

The cell surface protein CD93 is known to be involved in the regulation of phagocytosis and cell adhesion. Although typically membrane-bound, a soluble form of CD93 (sCD93) has recently been identified. Currently, however, the role of sCD93 in monocyte function is unknown. In the current study, we a...

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Veröffentlicht in:	The Journal of immunology (1950) 2010-10, Vol.185 (8), p.4921-4927
Hauptverfasser:	Jeon, Jae-Won, Jung, Joon-Goo, Shin, Eui-Cheol, Choi, Hye In, Kim, Ho Youn, Cho, Mi-La, Kim, Sun-Wha, Jang, Young-Soon, Sohn, Myung-Ho, Moon, Ji-Hyun, Cho, Young-Hun, Hoe, Kwang-Lae, Seo, Yeon-Soo, Park, Young Woo
Format:	Artikel
Sprache:	eng
Schlagworte:	Arthritis, Rheumatoid - immunology Arthritis, Rheumatoid - metabolism Cell Differentiation - immunology Cytokines - biosynthesis Enzyme-Linked Immunosorbent Assay Humans Inflammation - immunology Inflammation - metabolism Membrane Glycoproteins - immunology Membrane Glycoproteins - metabolism Monocytes - cytology Monocytes - immunology Monocytes - metabolism Receptors, Complement - immunology Receptors, Complement - metabolism Recombinant Proteins Reverse Transcriptase Polymerase Chain Reaction Synovial Fluid - immunology Synovial Fluid - metabolism Toll-Like Receptors - immunology Toll-Like Receptors - metabolism
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