TNF microsatellite alleles may confer protection against the development of lipodystrophy syndrome in Brazilian HIV patients

Summary The aim of this study was to evaluate the frequency of TNFa–e microsatellites and the promoter region (TNF‐308 and TNF‐238) in HIV/AIDS‐infected patients presenting or not lipodystrophy syndrome (LS). The design is the genetic case–control association study. Microsatellite and the TNF promot...

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Veröffentlicht in:	International journal of immunogenetics 2010-10, Vol.37 (5), p.379-385
Hauptverfasser:	Silva, M. M., Simões, R. T., Castelli, E. C., Mendes-Junior, C. T., Deghaide, N. H. S., Tsuda, L. C., Machado, A. A., Donadi, E. A., Fernandes, A. P. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Brazil Development Gel electrophoresis Gene Frequency Gene polymorphism Genetic Predisposition to Disease Genotype Haplotypes HIV Infections - complications HIV-Associated Lipodystrophy Syndrome - etiology HIV-Associated Lipodystrophy Syndrome - genetics Homozygotes Human immunodeficiency virus Humans Lipodystrophy Microsatellite Repeats - genetics Microsatellites Middle Aged Polymerase chain reaction Polymorphism, Genetic Promoter Regions, Genetic Promoters Tumor necrosis factor Tumor Necrosis Factor-alpha - genetics
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