Extraction and identification of three major aldose reductase inhibitors from Artemisia montana

Aldose reductase inhibitors (ARIs) provide an important therapeutic and preventive opportunity against hyperglycemia associated diabetic complications. The methanolic extracts of 12 species from the genus Artemisia exhibited significant in vitro rat lens AR (RLAR) inhibitory activities with IC50 val...

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Veröffentlicht in:	Food and chemical toxicology 2011-02, Vol.49 (2), p.376-384
Hauptverfasser:	Jung, Hyun Ah, Islam, M.D. Nurul, Kwon, Yong Soo, Jin, Seong Eun, Son, You Kyung, Park, Jin Ju, Sohn, Hee Sook, Choi, Jae Sue
Format:	Artikel
Sprache:	eng
Schlagworte:	aldehyde reductase Aldehyde Reductase - antagonists & inhibitors Aldose reductase Animals apigenin Artemisia Artemisia - chemistry Artemisia montana Biological and medical sciences Caffeoylquinic acid chlorogenic acid Compositae diabetic complications ethyl acetate Flavonoids - chemistry Flavonoids - pharmacology fractionation General pharmacology high performance liquid chromatography HPLC hyperglycemia Hyperoside Inhibitory Concentration 50 isoquercitrin Lens, Crystalline - enzymology luteolin Medical sciences Molecular Structure Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - chemistry Plant Extracts - pharmacology quercetin Rats Republic of Korea scopoletin spectroscopy umbelliferones
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