MHC class II risk haplotype associated with Canine chronic superficial keratitis in German Shepherd dogs

Canine chronic superficial keratitis (CSK) is an inflammatory ocular disease of an autoimmune origin leading to blindness if untreated. The main symptoms of CSK are progressive, bilateral vascularisation, fibrous tissue formation and pigmentation of the anterior corneal stroma. Although CSK is found...

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Veröffentlicht in:	Veterinary immunology and immunopathology 2011-03, Vol.140 (1), p.37-41
Hauptverfasser:	Jokinen, Päivi, Rusanen, Elina M., Kennedy, Lorna J., Lohi, Hannes
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Canis familiaris Chronic Disease Chronic superficial keratitis DLA Dog Diseases - epidemiology Dog Diseases - genetics Dogs Female Genes, MHC Class II German Shepherd dogs Haplotypes Histocompatibility Antigens Class II - genetics HLA-DQ alpha-Chains HLA-DQ Antigens - genetics HLA-DQ beta-Chains HLA-DR Antigens - genetics HLA-DRB1 Chains Homozygote Immune-mediated Keratitis - epidemiology Keratitis - genetics Keratitis - veterinary Major histocompatibility complex class II Male Odds Ratio Risk
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