In vitro photobiochemical characterization of sulfobutylether-β-cyclodextrin formulation of bufexamac

The present study aimed to modulate the photoreactivity of bufexamac, with a focus on photostability and phototoxicity, by forming an inclusion complex with sulfobutylether-β-cyclodextrin (SBECD). The photobiochemical properties of bufexamac were evaluated by reactive oxygen species (ROS) assay and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2011-06, Vol.55 (3), p.591-596
Hauptverfasser:	Seto, Yoshiki, Ochi, Masanori, Igarashi, Naoko, Inoue, Ryo, Oishi, Ami, Toida, Toshihiko, Yamada, Shizuo, Onoue, Satomi
Format:	Artikel
Sprache:	eng
Schlagworte:	absorption Animals beta-Cyclodextrins - chemistry beta-Cyclodextrins - radiation effects beta-Cyclodextrins - toxicity Binding, Competitive Bufexamac Bufexamac - chemistry Bufexamac - radiation effects Bufexamac - toxicity Circular Dichroism DNA - chemistry Drug Stability drugs Inclusion complex Male Molecular Structure Photolysis Photoreactivity photostability phototoxicity reactive oxygen species Reactive Oxygen Species - analysis Reactive oxygen species assay risk Salmon Spectrophotometry, Ultraviolet spectroscopy Spermatozoa - chemistry Sulfobutylether-β-cyclodextrin
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!