Design, synthesis and antifungal activities of novel pyrrole alkaloid analogs

A series of novel analogs of pyrrole alkaloid were designed and synthesized by a facile method and their structures were characterized by 1H NMR, 13C NMR and high-resolution mass spectrometry (HRMS). The structure of compound 2a was identified by 2D NMR including heteronuclear multiple-quantum coher...

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Veröffentlicht in:	European journal of medicinal chemistry 2011-05, Vol.46 (5), p.1463-1472
Hauptverfasser:	Wang, Ming-Zhong, Xu, Han, Liu, Tuan-Wei, Feng, Qi, Yu, Shu-Jing, Wang, Su-Hua, Li, Zheng-Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	2D NMR Alkaloids - chemical synthesis Alkaloids - chemistry Alkaloids - pharmacology Analogues Antifungal activities Antifungal Agents - chemical synthesis Antifungal Agents - chemistry Antifungal Agents - pharmacology Biological and medical sciences Chemical control Control Drug Design Fundamental and applied biological sciences. Psychology Fungal plant pathogens Fungi - drug effects Microbial Sensitivity Tests Molecular Structure Phytopathology. Animal pests. Plant and forest protection Pyrrole alkaloid Pyrroles - chemical synthesis Pyrroles - chemistry Pyrroles - pharmacology Stereoisomerism Structure-Activity Relationship
Online-Zugang:	Volltext
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