Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: Effects on axonal viability

Abstract Tau inclusions play a key role in the pathogenesis of tauopathies. Altered tau levels have been detected in retina and optic nerve of patients with glaucoma, suggesting the possibility of shared pathogenic mechanisms with tauopathies. Here we report that hyperphosphorylated transgenic tau a...

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