Hematological consequences of pandemic influenza H1N1 infection: a single center experience
Since its identification in April 2009, pandemic influenza H1N1 virus has affected thousands of people worldwide. Viruses, particularly Epstein-Barr virus, cytomegalovirus and parvovirus B19, may have diverse hematological consequences, including anemia, neutropenia, thrombocytopenia, lymphocytosis,...
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Veröffentlicht in: | Turkish journal of pediatrics 2010-11, Vol.52 (6), p.570-575 |
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creator | Unal, Sule Gökçe, Müge Aytaç-Elmas, Selin Karabulut, Erdem Altan, Ilhan Ozkaya-Parlakay, Aslinur Kara, Ateş Ceyhan, Mehmet Cengiz, Ali Bülent Tuncer, Murat Cetin, Mualla Gümrük, Fatma |
description | Since its identification in April 2009, pandemic influenza H1N1 virus has affected thousands of people worldwide. Viruses, particularly Epstein-Barr virus, cytomegalovirus and parvovirus B19, may have diverse hematological consequences, including anemia, neutropenia, thrombocytopenia, lymphocytosis, hemophagocytic lymphohistiocytosis, and coagulation abnormalities. In this study, a total of 31 consecutive pediatric patients, with and without chronic diseases, who had flu symptoms and were confirmed to have pandemic influenza, were evaluated for hematological consequences upon presentation to hospital. Eight (25.8%) patients had leukopenia and six (19.4%) had thrombocytopenia at the time of diagnosis of H1N1 infection. Pandemic influenza H1N1 infection may cause diverse hematological findings, including cytopenias and hemophagocytosis. |
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Viruses, particularly Epstein-Barr virus, cytomegalovirus and parvovirus B19, may have diverse hematological consequences, including anemia, neutropenia, thrombocytopenia, lymphocytosis, hemophagocytic lymphohistiocytosis, and coagulation abnormalities. In this study, a total of 31 consecutive pediatric patients, with and without chronic diseases, who had flu symptoms and were confirmed to have pandemic influenza, were evaluated for hematological consequences upon presentation to hospital. Eight (25.8%) patients had leukopenia and six (19.4%) had thrombocytopenia at the time of diagnosis of H1N1 infection. Pandemic influenza H1N1 infection may cause diverse hematological findings, including cytopenias and hemophagocytosis.</description><identifier>ISSN: 0041-4301</identifier><identifier>PMID: 21428187</identifier><language>eng</language><publisher>Turkey: Hacettepe University Faculty of Medicine</publisher><subject>Adolescent ; Child ; Child, Preschool ; Female ; Hematologic Diseases - etiology ; Humans ; Infant ; Influenza A Virus, H1N1 Subtype ; Influenza, Human - blood ; Influenza, Human - complications ; Influenza, Human - epidemiology ; Leukopenia - etiology ; Male ; Pandemics ; Thrombocytopenia - etiology</subject><ispartof>Turkish journal of pediatrics, 2010-11, Vol.52 (6), p.570-575</ispartof><rights>Copyright Hacettepe University Faculty of Medicine Nov/Dec 2010</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21428187$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Unal, Sule</creatorcontrib><creatorcontrib>Gökçe, Müge</creatorcontrib><creatorcontrib>Aytaç-Elmas, Selin</creatorcontrib><creatorcontrib>Karabulut, Erdem</creatorcontrib><creatorcontrib>Altan, Ilhan</creatorcontrib><creatorcontrib>Ozkaya-Parlakay, Aslinur</creatorcontrib><creatorcontrib>Kara, Ateş</creatorcontrib><creatorcontrib>Ceyhan, Mehmet</creatorcontrib><creatorcontrib>Cengiz, Ali Bülent</creatorcontrib><creatorcontrib>Tuncer, Murat</creatorcontrib><creatorcontrib>Cetin, Mualla</creatorcontrib><creatorcontrib>Gümrük, Fatma</creatorcontrib><title>Hematological consequences of pandemic influenza H1N1 infection: a single center experience</title><title>Turkish journal of pediatrics</title><addtitle>Turk J Pediatr</addtitle><description>Since its identification in April 2009, pandemic influenza H1N1 virus has affected thousands of people worldwide. Viruses, particularly Epstein-Barr virus, cytomegalovirus and parvovirus B19, may have diverse hematological consequences, including anemia, neutropenia, thrombocytopenia, lymphocytosis, hemophagocytic lymphohistiocytosis, and coagulation abnormalities. In this study, a total of 31 consecutive pediatric patients, with and without chronic diseases, who had flu symptoms and were confirmed to have pandemic influenza, were evaluated for hematological consequences upon presentation to hospital. Eight (25.8%) patients had leukopenia and six (19.4%) had thrombocytopenia at the time of diagnosis of H1N1 infection. Pandemic influenza H1N1 infection may cause diverse hematological findings, including cytopenias and hemophagocytosis.</description><subject>Adolescent</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Hematologic Diseases - etiology</subject><subject>Humans</subject><subject>Infant</subject><subject>Influenza A Virus, H1N1 Subtype</subject><subject>Influenza, Human - blood</subject><subject>Influenza, Human - complications</subject><subject>Influenza, Human - epidemiology</subject><subject>Leukopenia - etiology</subject><subject>Male</subject><subject>Pandemics</subject><subject>Thrombocytopenia - etiology</subject><issn>0041-4301</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpd0E1LxDAQBuAcFHdd_QsSvHgq5KtN4k0WdYVFL3ryUNJksmRpk9q0oP56u7hePA0zPLy8zAlaEiJoITihC3Se854QJomWZ2jBqGCKKrlE7xvozJjatAvWtNimmOFjgmgh4-Rxb6KDLlgcom_n87fBG_pMDyvYMaR4iw3OIe5awBbiCAOGzx6GcEi4QKfetBkuj3OF3h7uX9ebYvvy-LS-2xY943IsJCfEcSIaZ5WujPbEW2e859Y0wgtQ3pdAKK3KShsDUDpwrGGOV6BBa81X6OY3tx_S3D2PdReyhbY1EdKUa1UqqUQpyCyv_8l9moY4l5sRV5owLWd0dURT04Gr-yF0Zviq_57GfwCM9WiV</recordid><startdate>20101101</startdate><enddate>20101101</enddate><creator>Unal, Sule</creator><creator>Gökçe, Müge</creator><creator>Aytaç-Elmas, Selin</creator><creator>Karabulut, Erdem</creator><creator>Altan, Ilhan</creator><creator>Ozkaya-Parlakay, Aslinur</creator><creator>Kara, Ateş</creator><creator>Ceyhan, Mehmet</creator><creator>Cengiz, Ali Bülent</creator><creator>Tuncer, Murat</creator><creator>Cetin, Mualla</creator><creator>Gümrük, Fatma</creator><general>Hacettepe University Faculty of Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>4T-</scope><scope>4U-</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>EDSIH</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20101101</creationdate><title>Hematological consequences of pandemic influenza H1N1 infection: a single center experience</title><author>Unal, Sule ; 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subjects | Adolescent Child Child, Preschool Female Hematologic Diseases - etiology Humans Infant Influenza A Virus, H1N1 Subtype Influenza, Human - blood Influenza, Human - complications Influenza, Human - epidemiology Leukopenia - etiology Male Pandemics Thrombocytopenia - etiology |
title | Hematological consequences of pandemic influenza H1N1 infection: a single center experience |
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