Hematological consequences of pandemic influenza H1N1 infection: a single center experience

Since its identification in April 2009, pandemic influenza H1N1 virus has affected thousands of people worldwide. Viruses, particularly Epstein-Barr virus, cytomegalovirus and parvovirus B19, may have diverse hematological consequences, including anemia, neutropenia, thrombocytopenia, lymphocytosis,...

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Veröffentlicht in:Turkish journal of pediatrics 2010-11, Vol.52 (6), p.570-575
Hauptverfasser: Unal, Sule, Gökçe, Müge, Aytaç-Elmas, Selin, Karabulut, Erdem, Altan, Ilhan, Ozkaya-Parlakay, Aslinur, Kara, Ateş, Ceyhan, Mehmet, Cengiz, Ali Bülent, Tuncer, Murat, Cetin, Mualla, Gümrük, Fatma
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container_end_page 575
container_issue 6
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container_title Turkish journal of pediatrics
container_volume 52
creator Unal, Sule
Gökçe, Müge
Aytaç-Elmas, Selin
Karabulut, Erdem
Altan, Ilhan
Ozkaya-Parlakay, Aslinur
Kara, Ateş
Ceyhan, Mehmet
Cengiz, Ali Bülent
Tuncer, Murat
Cetin, Mualla
Gümrük, Fatma
description Since its identification in April 2009, pandemic influenza H1N1 virus has affected thousands of people worldwide. Viruses, particularly Epstein-Barr virus, cytomegalovirus and parvovirus B19, may have diverse hematological consequences, including anemia, neutropenia, thrombocytopenia, lymphocytosis, hemophagocytic lymphohistiocytosis, and coagulation abnormalities. In this study, a total of 31 consecutive pediatric patients, with and without chronic diseases, who had flu symptoms and were confirmed to have pandemic influenza, were evaluated for hematological consequences upon presentation to hospital. Eight (25.8%) patients had leukopenia and six (19.4%) had thrombocytopenia at the time of diagnosis of H1N1 infection. Pandemic influenza H1N1 infection may cause diverse hematological findings, including cytopenias and hemophagocytosis.
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Viruses, particularly Epstein-Barr virus, cytomegalovirus and parvovirus B19, may have diverse hematological consequences, including anemia, neutropenia, thrombocytopenia, lymphocytosis, hemophagocytic lymphohistiocytosis, and coagulation abnormalities. In this study, a total of 31 consecutive pediatric patients, with and without chronic diseases, who had flu symptoms and were confirmed to have pandemic influenza, were evaluated for hematological consequences upon presentation to hospital. Eight (25.8%) patients had leukopenia and six (19.4%) had thrombocytopenia at the time of diagnosis of H1N1 infection. 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subjects Adolescent
Child
Child, Preschool
Female
Hematologic Diseases - etiology
Humans
Infant
Influenza A Virus, H1N1 Subtype
Influenza, Human - blood
Influenza, Human - complications
Influenza, Human - epidemiology
Leukopenia - etiology
Male
Pandemics
Thrombocytopenia - etiology
title Hematological consequences of pandemic influenza H1N1 infection: a single center experience
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