Lewis Acid Catalyzed Benzylic C−H Bond Functionalization of Azaarenes: Addition to Enones

A Lewis acid catalyzed benzylic C−H bond functionalization of alkyl-substituted azaarenes is described. Sc(OTf)3 and Y(OTf)3 promoted the direct addition of alkyl-substituted azaarenes and benzoxazole to enones and an α,β-unsaturated N-acylpyrrole. Products were obtained in 60−96% yield.

Bibliographische Detailangaben

Veröffentlicht in:	Organic letters 2011-04, Vol.13 (7), p.1706-1709
Hauptverfasser:	Komai, Hirotomo, Yoshino, Tatsuhiko, Matsunaga, Shigeki, Kanai, Motomu
Format:	Artikel
Sprache:	eng
Schlagworte:	Aza Compounds - chemistry Benzene - chemistry Carbon - chemistry Catalysis Hydrogen - chemistry Lewis Acids - chemistry Molecular Structure
Online-Zugang:	Volltext
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