Sigmoid Diverticulitis in Young Patients—A More Aggressive Disease than in Older Patients?
Introduction There is controversy over whether sigmoid diverticulitis (SD) is more aggressive with a higher risk of perforation in younger than in older patients. The aim of this study was to assess the clinical presentation and outcome of patients ≤40 and >40 years old with acute diverticulitis....
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Veröffentlicht in: | Journal of gastrointestinal surgery 2011-04, Vol.15 (4), p.667-674 |
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description | Introduction
There is controversy over whether sigmoid diverticulitis (SD) is more aggressive with a higher risk of perforation in younger than in older patients. The aim of this study was to assess the clinical presentation and outcome of patients ≤40 and >40 years old with acute diverticulitis.
Patients and Methods
Consecutive admissions of all patients with acute SD were prospectively recruited from January 1998 to June 2010.
Results
A total of 1,019 patients were included: 513 (69 ≤40 years and 444 >40 years) presented with their first episode, while 506 (20 ≤40 years, 486 >40 years) had a prior history of SD. The percentage of patients with severe SD did not differ between the two age groups either for the first (covered perforation, 30.4% vs. 29.5%,
p
= 0.875; free perforation, 26.1% vs. 23.9%,
p
= 0.69) or for the recurrent episode (covered perforation, 15% vs. 8.2%,
p
= 0.287; free perforation, 5% vs. 4.1%,
p
= 0.846). Furthermore, the rate of emergency surgery did not differ between both age groups either for the first (26.1% vs. 23.9%,
p
= 0.690) or the recurrent episode (5% vs. 4.1%,
p
= 0.846). No differences in the rate of Hartmann’s procedure (52.6% vs. 68.3%,
p
= 0.180) and failure of conservative treatment (3.4% vs. 4.9%,
p
= 0.607) were observed between younger and older patients.
Conclusion
Acute SD in younger patients is not more aggressive and has no higher risk of perforation or need for emergency surgery compared to older patients. |
doi_str_mv | 10.1007/s11605-011-1457-2 |
format | Article |
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There is controversy over whether sigmoid diverticulitis (SD) is more aggressive with a higher risk of perforation in younger than in older patients. The aim of this study was to assess the clinical presentation and outcome of patients ≤40 and >40 years old with acute diverticulitis.
Patients and Methods
Consecutive admissions of all patients with acute SD were prospectively recruited from January 1998 to June 2010.
Results
A total of 1,019 patients were included: 513 (69 ≤40 years and 444 >40 years) presented with their first episode, while 506 (20 ≤40 years, 486 >40 years) had a prior history of SD. The percentage of patients with severe SD did not differ between the two age groups either for the first (covered perforation, 30.4% vs. 29.5%,
p
= 0.875; free perforation, 26.1% vs. 23.9%,
p
= 0.69) or for the recurrent episode (covered perforation, 15% vs. 8.2%,
p
= 0.287; free perforation, 5% vs. 4.1%,
p
= 0.846). Furthermore, the rate of emergency surgery did not differ between both age groups either for the first (26.1% vs. 23.9%,
p
= 0.690) or the recurrent episode (5% vs. 4.1%,
p
= 0.846). No differences in the rate of Hartmann’s procedure (52.6% vs. 68.3%,
p
= 0.180) and failure of conservative treatment (3.4% vs. 4.9%,
p
= 0.607) were observed between younger and older patients.
Conclusion
Acute SD in younger patients is not more aggressive and has no higher risk of perforation or need for emergency surgery compared to older patients.</description><identifier>ISSN: 1091-255X</identifier><identifier>EISSN: 1873-4626</identifier><identifier>DOI: 10.1007/s11605-011-1457-2</identifier><identifier>PMID: 21318443</identifier><language>eng</language><publisher>New York: Springer-Verlag</publisher><subject>Abdomen ; Abscesses ; Acute Disease ; Adult ; Age Factors ; Age groups ; Antibiotics ; Colorectal cancer ; Disease ; Diverticulitis ; Diverticulitis - complications ; Diverticulitis - diagnostic imaging ; Diverticulitis - surgery ; Female ; Gastroenterology ; Humans ; Inflammation ; Intestinal Perforation - etiology ; Laparoscopy ; Male ; Medical imaging ; Medicine ; Medicine & Public Health ; Middle Aged ; Morphology ; Original Article ; Patients ; Peritonitis ; Recurrence ; Sigmoid Diseases - complications ; Sigmoid Diseases - diagnostic imaging ; Sigmoid Diseases - surgery ; Surgery ; Thoracic surgery ; Tomography, X-Ray Computed</subject><ispartof>Journal of gastrointestinal surgery, 2011-04, Vol.15 (4), p.667-674</ispartof><rights>The Society for Surgery of the Alimentary Tract 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c371t-23519ecd345652f78b5654ddc9335ef0151723dc0f8bc0328c3eba7ccb90422b3</citedby><cites>FETCH-LOGICAL-c371t-23519ecd345652f78b5654ddc9335ef0151723dc0f8bc0328c3eba7ccb90422b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11605-011-1457-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11605-011-1457-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21318443$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ritz, Jörg-Peter</creatorcontrib><creatorcontrib>Lehmann, Kai S.</creatorcontrib><creatorcontrib>Stroux, Andrea</creatorcontrib><creatorcontrib>Buhr, Heinz J.</creatorcontrib><creatorcontrib>Holmer, Christoph</creatorcontrib><title>Sigmoid Diverticulitis in Young Patients—A More Aggressive Disease than in Older Patients?</title><title>Journal of gastrointestinal surgery</title><addtitle>J Gastrointest Surg</addtitle><addtitle>J Gastrointest Surg</addtitle><description>Introduction
There is controversy over whether sigmoid diverticulitis (SD) is more aggressive with a higher risk of perforation in younger than in older patients. The aim of this study was to assess the clinical presentation and outcome of patients ≤40 and >40 years old with acute diverticulitis.
Patients and Methods
Consecutive admissions of all patients with acute SD were prospectively recruited from January 1998 to June 2010.
Results
A total of 1,019 patients were included: 513 (69 ≤40 years and 444 >40 years) presented with their first episode, while 506 (20 ≤40 years, 486 >40 years) had a prior history of SD. The percentage of patients with severe SD did not differ between the two age groups either for the first (covered perforation, 30.4% vs. 29.5%,
p
= 0.875; free perforation, 26.1% vs. 23.9%,
p
= 0.69) or for the recurrent episode (covered perforation, 15% vs. 8.2%,
p
= 0.287; free perforation, 5% vs. 4.1%,
p
= 0.846). Furthermore, the rate of emergency surgery did not differ between both age groups either for the first (26.1% vs. 23.9%,
p
= 0.690) or the recurrent episode (5% vs. 4.1%,
p
= 0.846). No differences in the rate of Hartmann’s procedure (52.6% vs. 68.3%,
p
= 0.180) and failure of conservative treatment (3.4% vs. 4.9%,
p
= 0.607) were observed between younger and older patients.
Conclusion
Acute SD in younger patients is not more aggressive and has no higher risk of perforation or need for emergency surgery compared to older patients.</description><subject>Abdomen</subject><subject>Abscesses</subject><subject>Acute Disease</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Age groups</subject><subject>Antibiotics</subject><subject>Colorectal cancer</subject><subject>Disease</subject><subject>Diverticulitis</subject><subject>Diverticulitis - complications</subject><subject>Diverticulitis - diagnostic imaging</subject><subject>Diverticulitis - surgery</subject><subject>Female</subject><subject>Gastroenterology</subject><subject>Humans</subject><subject>Inflammation</subject><subject>Intestinal Perforation - etiology</subject><subject>Laparoscopy</subject><subject>Male</subject><subject>Medical imaging</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Morphology</subject><subject>Original Article</subject><subject>Patients</subject><subject>Peritonitis</subject><subject>Recurrence</subject><subject>Sigmoid Diseases - complications</subject><subject>Sigmoid Diseases - diagnostic imaging</subject><subject>Sigmoid Diseases - surgery</subject><subject>Surgery</subject><subject>Thoracic surgery</subject><subject>Tomography, X-Ray Computed</subject><issn>1091-255X</issn><issn>1873-4626</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kM1KxDAURoMojo4-gBspuHBVzU2aSWYlg_-gKKigIIQ2va2RTjsmreDOh_AJfRJTZhQRXN1Azvfd5BCyBXQPKJX7HmBERUwBYkiEjNkSWQMleZyM2Gg5nOkYYibE_YCse_9MKUgKapUMGHBQScLXyOONLaeNzaMj-4qutaarbGt9ZOvooenqMrpOW4t16z_fPybRZeMwmpSlQ-8DH0IeU49R-5TWfeSqytH9RA42yEqRVh43F3NI7k6Obw_P4our0_PDyUVsuIQ2ZlzAGE3OEzESrJAqCzPJczPmXGBBQYBkPDe0UJmhnCnDMUulMdmYJoxlfEh2570z17x06Fs9td5gVaU1Np3XSigpZf_hIdn5Qz43navD43SQ1a8XigUK5pRxjfcOCz1zdpq6twDp3ryem9fBvO7N6z6zvWjusinmP4lv1QFgc8CHq7pE93v1f61fY76OBA</recordid><startdate>20110401</startdate><enddate>20110401</enddate><creator>Ritz, Jörg-Peter</creator><creator>Lehmann, Kai S.</creator><creator>Stroux, Andrea</creator><creator>Buhr, Heinz J.</creator><creator>Holmer, Christoph</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>20110401</creationdate><title>Sigmoid Diverticulitis in Young Patients—A More Aggressive Disease than in Older Patients?</title><author>Ritz, Jörg-Peter ; Lehmann, Kai S. ; Stroux, Andrea ; Buhr, Heinz J. ; Holmer, Christoph</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c371t-23519ecd345652f78b5654ddc9335ef0151723dc0f8bc0328c3eba7ccb90422b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Abdomen</topic><topic>Abscesses</topic><topic>Acute Disease</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Age groups</topic><topic>Antibiotics</topic><topic>Colorectal cancer</topic><topic>Disease</topic><topic>Diverticulitis</topic><topic>Diverticulitis - complications</topic><topic>Diverticulitis - diagnostic imaging</topic><topic>Diverticulitis - surgery</topic><topic>Female</topic><topic>Gastroenterology</topic><topic>Humans</topic><topic>Inflammation</topic><topic>Intestinal Perforation - etiology</topic><topic>Laparoscopy</topic><topic>Male</topic><topic>Medical imaging</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Morphology</topic><topic>Original Article</topic><topic>Patients</topic><topic>Peritonitis</topic><topic>Recurrence</topic><topic>Sigmoid Diseases - complications</topic><topic>Sigmoid Diseases - diagnostic imaging</topic><topic>Sigmoid Diseases - surgery</topic><topic>Surgery</topic><topic>Thoracic surgery</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ritz, Jörg-Peter</creatorcontrib><creatorcontrib>Lehmann, Kai S.</creatorcontrib><creatorcontrib>Stroux, Andrea</creatorcontrib><creatorcontrib>Buhr, Heinz J.</creatorcontrib><creatorcontrib>Holmer, Christoph</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of gastrointestinal surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ritz, Jörg-Peter</au><au>Lehmann, Kai S.</au><au>Stroux, Andrea</au><au>Buhr, Heinz J.</au><au>Holmer, Christoph</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sigmoid Diverticulitis in Young Patients—A More Aggressive Disease than in Older Patients?</atitle><jtitle>Journal of gastrointestinal surgery</jtitle><stitle>J Gastrointest Surg</stitle><addtitle>J Gastrointest Surg</addtitle><date>2011-04-01</date><risdate>2011</risdate><volume>15</volume><issue>4</issue><spage>667</spage><epage>674</epage><pages>667-674</pages><issn>1091-255X</issn><eissn>1873-4626</eissn><abstract>Introduction
There is controversy over whether sigmoid diverticulitis (SD) is more aggressive with a higher risk of perforation in younger than in older patients. The aim of this study was to assess the clinical presentation and outcome of patients ≤40 and >40 years old with acute diverticulitis.
Patients and Methods
Consecutive admissions of all patients with acute SD were prospectively recruited from January 1998 to June 2010.
Results
A total of 1,019 patients were included: 513 (69 ≤40 years and 444 >40 years) presented with their first episode, while 506 (20 ≤40 years, 486 >40 years) had a prior history of SD. The percentage of patients with severe SD did not differ between the two age groups either for the first (covered perforation, 30.4% vs. 29.5%,
p
= 0.875; free perforation, 26.1% vs. 23.9%,
p
= 0.69) or for the recurrent episode (covered perforation, 15% vs. 8.2%,
p
= 0.287; free perforation, 5% vs. 4.1%,
p
= 0.846). Furthermore, the rate of emergency surgery did not differ between both age groups either for the first (26.1% vs. 23.9%,
p
= 0.690) or the recurrent episode (5% vs. 4.1%,
p
= 0.846). No differences in the rate of Hartmann’s procedure (52.6% vs. 68.3%,
p
= 0.180) and failure of conservative treatment (3.4% vs. 4.9%,
p
= 0.607) were observed between younger and older patients.
Conclusion
Acute SD in younger patients is not more aggressive and has no higher risk of perforation or need for emergency surgery compared to older patients.</abstract><cop>New York</cop><pub>Springer-Verlag</pub><pmid>21318443</pmid><doi>10.1007/s11605-011-1457-2</doi><tpages>8</tpages></addata></record> |
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subjects | Abdomen Abscesses Acute Disease Adult Age Factors Age groups Antibiotics Colorectal cancer Disease Diverticulitis Diverticulitis - complications Diverticulitis - diagnostic imaging Diverticulitis - surgery Female Gastroenterology Humans Inflammation Intestinal Perforation - etiology Laparoscopy Male Medical imaging Medicine Medicine & Public Health Middle Aged Morphology Original Article Patients Peritonitis Recurrence Sigmoid Diseases - complications Sigmoid Diseases - diagnostic imaging Sigmoid Diseases - surgery Surgery Thoracic surgery Tomography, X-Ray Computed |
title | Sigmoid Diverticulitis in Young Patients—A More Aggressive Disease than in Older Patients? |
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