Sigmoid Diverticulitis in Young Patients—A More Aggressive Disease than in Older Patients?

Introduction There is controversy over whether sigmoid diverticulitis (SD) is more aggressive with a higher risk of perforation in younger than in older patients. The aim of this study was to assess the clinical presentation and outcome of patients ≤40 and >40 years old with acute diverticulitis....

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Veröffentlicht in:Journal of gastrointestinal surgery 2011-04, Vol.15 (4), p.667-674
Hauptverfasser: Ritz, Jörg-Peter, Lehmann, Kai S., Stroux, Andrea, Buhr, Heinz J., Holmer, Christoph
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container_issue 4
container_start_page 667
container_title Journal of gastrointestinal surgery
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creator Ritz, Jörg-Peter
Lehmann, Kai S.
Stroux, Andrea
Buhr, Heinz J.
Holmer, Christoph
description Introduction There is controversy over whether sigmoid diverticulitis (SD) is more aggressive with a higher risk of perforation in younger than in older patients. The aim of this study was to assess the clinical presentation and outcome of patients ≤40 and >40 years old with acute diverticulitis. Patients and Methods Consecutive admissions of all patients with acute SD were prospectively recruited from January 1998 to June 2010. Results A total of 1,019 patients were included: 513 (69 ≤40 years and 444 >40 years) presented with their first episode, while 506 (20 ≤40 years, 486 >40 years) had a prior history of SD. The percentage of patients with severe SD did not differ between the two age groups either for the first (covered perforation, 30.4% vs. 29.5%, p  = 0.875; free perforation, 26.1% vs. 23.9%, p  = 0.69) or for the recurrent episode (covered perforation, 15% vs. 8.2%, p  = 0.287; free perforation, 5% vs. 4.1%, p  = 0.846). Furthermore, the rate of emergency surgery did not differ between both age groups either for the first (26.1% vs. 23.9%, p  = 0.690) or the recurrent episode (5% vs. 4.1%, p  = 0.846). No differences in the rate of Hartmann’s procedure (52.6% vs. 68.3%, p  = 0.180) and failure of conservative treatment (3.4% vs. 4.9%, p  = 0.607) were observed between younger and older patients. Conclusion Acute SD in younger patients is not more aggressive and has no higher risk of perforation or need for emergency surgery compared to older patients.
doi_str_mv 10.1007/s11605-011-1457-2
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The aim of this study was to assess the clinical presentation and outcome of patients ≤40 and &gt;40 years old with acute diverticulitis. Patients and Methods Consecutive admissions of all patients with acute SD were prospectively recruited from January 1998 to June 2010. Results A total of 1,019 patients were included: 513 (69 ≤40 years and 444 &gt;40 years) presented with their first episode, while 506 (20 ≤40 years, 486 &gt;40 years) had a prior history of SD. The percentage of patients with severe SD did not differ between the two age groups either for the first (covered perforation, 30.4% vs. 29.5%, p  = 0.875; free perforation, 26.1% vs. 23.9%, p  = 0.69) or for the recurrent episode (covered perforation, 15% vs. 8.2%, p  = 0.287; free perforation, 5% vs. 4.1%, p  = 0.846). Furthermore, the rate of emergency surgery did not differ between both age groups either for the first (26.1% vs. 23.9%, p  = 0.690) or the recurrent episode (5% vs. 4.1%, p  = 0.846). No differences in the rate of Hartmann’s procedure (52.6% vs. 68.3%, p  = 0.180) and failure of conservative treatment (3.4% vs. 4.9%, p  = 0.607) were observed between younger and older patients. Conclusion Acute SD in younger patients is not more aggressive and has no higher risk of perforation or need for emergency surgery compared to older patients.</description><identifier>ISSN: 1091-255X</identifier><identifier>EISSN: 1873-4626</identifier><identifier>DOI: 10.1007/s11605-011-1457-2</identifier><identifier>PMID: 21318443</identifier><language>eng</language><publisher>New York: Springer-Verlag</publisher><subject>Abdomen ; Abscesses ; Acute Disease ; Adult ; Age Factors ; Age groups ; Antibiotics ; Colorectal cancer ; Disease ; Diverticulitis ; Diverticulitis - complications ; Diverticulitis - diagnostic imaging ; Diverticulitis - surgery ; Female ; Gastroenterology ; Humans ; Inflammation ; Intestinal Perforation - etiology ; Laparoscopy ; Male ; Medical imaging ; Medicine ; Medicine &amp; Public Health ; Middle Aged ; Morphology ; Original Article ; Patients ; Peritonitis ; Recurrence ; Sigmoid Diseases - complications ; Sigmoid Diseases - diagnostic imaging ; Sigmoid Diseases - surgery ; Surgery ; Thoracic surgery ; Tomography, X-Ray Computed</subject><ispartof>Journal of gastrointestinal surgery, 2011-04, Vol.15 (4), p.667-674</ispartof><rights>The Society for Surgery of the Alimentary Tract 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c371t-23519ecd345652f78b5654ddc9335ef0151723dc0f8bc0328c3eba7ccb90422b3</citedby><cites>FETCH-LOGICAL-c371t-23519ecd345652f78b5654ddc9335ef0151723dc0f8bc0328c3eba7ccb90422b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11605-011-1457-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11605-011-1457-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21318443$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ritz, Jörg-Peter</creatorcontrib><creatorcontrib>Lehmann, Kai S.</creatorcontrib><creatorcontrib>Stroux, Andrea</creatorcontrib><creatorcontrib>Buhr, Heinz J.</creatorcontrib><creatorcontrib>Holmer, Christoph</creatorcontrib><title>Sigmoid Diverticulitis in Young Patients—A More Aggressive Disease than in Older Patients?</title><title>Journal of gastrointestinal surgery</title><addtitle>J Gastrointest Surg</addtitle><addtitle>J Gastrointest Surg</addtitle><description>Introduction There is controversy over whether sigmoid diverticulitis (SD) is more aggressive with a higher risk of perforation in younger than in older patients. The aim of this study was to assess the clinical presentation and outcome of patients ≤40 and &gt;40 years old with acute diverticulitis. Patients and Methods Consecutive admissions of all patients with acute SD were prospectively recruited from January 1998 to June 2010. Results A total of 1,019 patients were included: 513 (69 ≤40 years and 444 &gt;40 years) presented with their first episode, while 506 (20 ≤40 years, 486 &gt;40 years) had a prior history of SD. The percentage of patients with severe SD did not differ between the two age groups either for the first (covered perforation, 30.4% vs. 29.5%, p  = 0.875; free perforation, 26.1% vs. 23.9%, p  = 0.69) or for the recurrent episode (covered perforation, 15% vs. 8.2%, p  = 0.287; free perforation, 5% vs. 4.1%, p  = 0.846). Furthermore, the rate of emergency surgery did not differ between both age groups either for the first (26.1% vs. 23.9%, p  = 0.690) or the recurrent episode (5% vs. 4.1%, p  = 0.846). No differences in the rate of Hartmann’s procedure (52.6% vs. 68.3%, p  = 0.180) and failure of conservative treatment (3.4% vs. 4.9%, p  = 0.607) were observed between younger and older patients. 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Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of gastrointestinal surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ritz, Jörg-Peter</au><au>Lehmann, Kai S.</au><au>Stroux, Andrea</au><au>Buhr, Heinz J.</au><au>Holmer, Christoph</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sigmoid Diverticulitis in Young Patients—A More Aggressive Disease than in Older Patients?</atitle><jtitle>Journal of gastrointestinal surgery</jtitle><stitle>J Gastrointest Surg</stitle><addtitle>J Gastrointest Surg</addtitle><date>2011-04-01</date><risdate>2011</risdate><volume>15</volume><issue>4</issue><spage>667</spage><epage>674</epage><pages>667-674</pages><issn>1091-255X</issn><eissn>1873-4626</eissn><abstract>Introduction There is controversy over whether sigmoid diverticulitis (SD) is more aggressive with a higher risk of perforation in younger than in older patients. The aim of this study was to assess the clinical presentation and outcome of patients ≤40 and &gt;40 years old with acute diverticulitis. Patients and Methods Consecutive admissions of all patients with acute SD were prospectively recruited from January 1998 to June 2010. Results A total of 1,019 patients were included: 513 (69 ≤40 years and 444 &gt;40 years) presented with their first episode, while 506 (20 ≤40 years, 486 &gt;40 years) had a prior history of SD. The percentage of patients with severe SD did not differ between the two age groups either for the first (covered perforation, 30.4% vs. 29.5%, p  = 0.875; free perforation, 26.1% vs. 23.9%, p  = 0.69) or for the recurrent episode (covered perforation, 15% vs. 8.2%, p  = 0.287; free perforation, 5% vs. 4.1%, p  = 0.846). Furthermore, the rate of emergency surgery did not differ between both age groups either for the first (26.1% vs. 23.9%, p  = 0.690) or the recurrent episode (5% vs. 4.1%, p  = 0.846). No differences in the rate of Hartmann’s procedure (52.6% vs. 68.3%, p  = 0.180) and failure of conservative treatment (3.4% vs. 4.9%, p  = 0.607) were observed between younger and older patients. Conclusion Acute SD in younger patients is not more aggressive and has no higher risk of perforation or need for emergency surgery compared to older patients.</abstract><cop>New York</cop><pub>Springer-Verlag</pub><pmid>21318443</pmid><doi>10.1007/s11605-011-1457-2</doi><tpages>8</tpages></addata></record>
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subjects Abdomen
Abscesses
Acute Disease
Adult
Age Factors
Age groups
Antibiotics
Colorectal cancer
Disease
Diverticulitis
Diverticulitis - complications
Diverticulitis - diagnostic imaging
Diverticulitis - surgery
Female
Gastroenterology
Humans
Inflammation
Intestinal Perforation - etiology
Laparoscopy
Male
Medical imaging
Medicine
Medicine & Public Health
Middle Aged
Morphology
Original Article
Patients
Peritonitis
Recurrence
Sigmoid Diseases - complications
Sigmoid Diseases - diagnostic imaging
Sigmoid Diseases - surgery
Surgery
Thoracic surgery
Tomography, X-Ray Computed
title Sigmoid Diverticulitis in Young Patients—A More Aggressive Disease than in Older Patients?
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