HLA-A, -B, -C, -DQB1, and -DRB1,3,4,5 allele and haplotype frequencies in the Costa Rica Central Valley Population and its relationship to worldwide populations

Abstract The human leukocyte antigen (HLA) system is the most polymorphic in humans. Its allele, genotype, and haplotype frequencies vary significantly among different populations. Molecular typing data on HLA are necessary for the development of stem cell donor registries, cord blood banks, HLA–dis...

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Veröffentlicht in:	Human immunology 2011, Vol.72 (1), p.80-86
Hauptverfasser:	Arrieta-Bolaños, Esteban, Maldonado-Torres, Hazael, Dimitriu, Oana, Hoddinott, Michael A, Fowles, Finnuala, Shah, Anila, Órlich-Pérez, Priscilla, McWhinnie, Alasdair J, Alfaro-Bourrouet, Wilbert, Buján-Boza, Willem, Little, Ann-Margaret, Salazar-Sánchez, Lizbeth, Madrigal, J. Alejandro
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Analysis of Variance Anthropology study Cluster Analysis Costa Rica Costa Rica Central Valley Population Frequencies Gene Frequency Haplotypes Hematopoietic stem cell donor registry Histocompatibility Antigens Class I - genetics Histocompatibility Antigens Class II - genetics Histocompatibility Testing Human leukocyte antigen Humans Linkage Disequilibrium - genetics Population Groups - genetics
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