Chronic exposure to fluoxetine (Prozac) causes developmental delays in Rana pipiens larvae

Selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine, are among the many pharmaceuticals detected in aquatic ecosystems. Although the acute effects of SSRIs on select organisms have been reported, little is understood about the chronic effects of these drugs on amphibians, which are p...

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Veröffentlicht in:	Environmental toxicology and chemistry 2010-12, Vol.29 (12), p.2845-2850
Hauptverfasser:	Foster, Hannah R., Burton, G. Allen, Basu, Niladri, Werner, Earl E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities, Drug-Induced - etiology Amphibian Amphibians Animals Antidepressants Aquatic ecosystems Arrays chemistry chronic exposure Control equipment Delay Dose-Response Relationship, Drug Ecology ecotoxicology Environment Exposure fluoxetine Fluoxetine - toxicity food intake Frogs Inhibitor drugs Inhibitors Larva - drug effects Larva - growth & development Larvae Lithobates pipiens Metamorphosis Organisms Outdoor Pharmaceuticals Rana pipiens Rana pipiens - abnormalities Rana pipiens - growth & development Reptiles & amphibians Selective serotonin reuptake inhibitor Serotonin Serotonin Uptake Inhibitors - toxicity Toxicity Toxicity Tests, Chronic Toxicology Water Pollutants, Chemical - toxicity weight gain
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