Cell surface heat shock protein 90 modulates prostate cancer cell adhesion and invasion through the integrin-β1/ focal adhesion kinase/c-Src signaling pathway

Heat shock protein (Hsp) 90 is a molecular chaperone that maintains the active conformation and function of numerous client oncoproteins in cancer cells. Hsp90 has also been detected on the plasma membrane of cells, and its expression has been suggested to correlate with metastatic potential. We stu...

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