Frequency and impact of symptoms experienced by patients with systemic sclerosis: results from a Canadian National Survey
Knowledge about the range of symptoms experienced by patients with SSc, and their impact on daily functioning is limited. The objective of the present study was to identify symptoms of SSc that patients rated as frequent and that highly impacted their ability to carry out daily activities. A total o...
Gespeichert in:
| Veröffentlicht in: | Rheumatology (Oxford, England) England), 2011-04, Vol.50 (4), p.762-767 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 767 |
|---|---|
| container_issue | 4 |
| container_start_page | 762 |
| container_title | Rheumatology (Oxford, England) |
| container_volume | 50 |
| creator | BASSEL, Marielle HUDSON, Marie TAILLEFER, Suzanne S SCHIEIR, Orit BARON, Murray THOMBS, Brett D |
| description | Knowledge about the range of symptoms experienced by patients with SSc, and their impact on daily functioning is limited. The objective of the present study was to identify symptoms of SSc that patients rated as frequent and that highly impacted their ability to carry out daily activities.
A total of 464 persons with SSc responded to the Canadian Scleroderma Patient Survey of Health Concerns and Research Priorities, including questions regarding the frequency and impact of 69 SSc symptoms. Descriptive analyses were performed dichotomizing symptom frequencies as never or rarely vs sometimes, most of the time or always and symptom impact on daily activities as no or minimal impact vs moderate to severe impact.
The five highest rated symptoms in terms of frequency and moderate to severe impact on daily activities, respectively, were: fatigue (89 and 72%), RP (86 and 67%), hand stiffness (81 and 59%), joint pain (81 and 64%) and difficulty sleeping (76 and 59%). In addition to these symptoms, items related to decreased hand function (difficulty making a fist and difficulty holding objects) and pain (muscle pain and joint tenderness) were frequently endorsed and commonly associated with moderate to severe impact on daily activities.
This study confirmed the importance for quality of life of core symptoms of SSc, such as pain, fatigue and limitations in hand function. It also identified areas with very little research, such as sleep problems, that appear to play important roles in daily functioning, and that merit more focused study. |
| doi_str_mv | 10.1093/rheumatology/keq310 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_858282985</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>858282985</sourcerecordid><originalsourceid>FETCH-LOGICAL-c379t-78681c051160e191cf3a59e7c66011c09b32b2765f45205b7e266f252cb770d73</originalsourceid><addsrcrecordid>eNpNkEtP3TAQhS0E4lV-QaXKG9TVBT8SO-muuioPCcGi7TpynEkxjePgcSj59xjdC2U1M5rvjOYcQj5zdsZZLc_jPczepDCEP8v5X3iUnO2QQ14osWJSit33XhQH5AjxgTFWclntkwPBeVGLoj4ky0WExxlGu1AzdtT5ydhEQ09x8VMKHik8TxBdJqCj7UInk_KQkP5z6T5TmMA7S9EOEAM6_EYj4DxkoI_BU0PXZjSdMyO9zcowmoH-nOMTLJ_IXm8GhJNtPSa_L378Wl-tbu4ur9ffb1ZW6jqtdKUqbvPjXDHgNbe9NGUN2irFeF7UrRSt0Krsi1KwstUglOpFKWyrNeu0PCZfN3enGLJTTI13aGEYzAhhxqYqK1GJuiozKTekzU4wQt9M0XkTl4az5jXy5mPkzSbyrPqyvT-3Hrp3zVvGGTjdAgatGfpoRuvwP1cwXmhVyBeSu5AU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>858282985</pqid></control><display><type>article</type><title>Frequency and impact of symptoms experienced by patients with systemic sclerosis: results from a Canadian National Survey</title><source>MEDLINE</source><source>Oxford Journals - Connect here FIRST to enable access</source><source>Alma/SFX Local Collection</source><creator>BASSEL, Marielle ; HUDSON, Marie ; TAILLEFER, Suzanne S ; SCHIEIR, Orit ; BARON, Murray ; THOMBS, Brett D</creator><creatorcontrib>BASSEL, Marielle ; HUDSON, Marie ; TAILLEFER, Suzanne S ; SCHIEIR, Orit ; BARON, Murray ; THOMBS, Brett D</creatorcontrib><description>Knowledge about the range of symptoms experienced by patients with SSc, and their impact on daily functioning is limited. The objective of the present study was to identify symptoms of SSc that patients rated as frequent and that highly impacted their ability to carry out daily activities.
A total of 464 persons with SSc responded to the Canadian Scleroderma Patient Survey of Health Concerns and Research Priorities, including questions regarding the frequency and impact of 69 SSc symptoms. Descriptive analyses were performed dichotomizing symptom frequencies as never or rarely vs sometimes, most of the time or always and symptom impact on daily activities as no or minimal impact vs moderate to severe impact.
The five highest rated symptoms in terms of frequency and moderate to severe impact on daily activities, respectively, were: fatigue (89 and 72%), RP (86 and 67%), hand stiffness (81 and 59%), joint pain (81 and 64%) and difficulty sleeping (76 and 59%). In addition to these symptoms, items related to decreased hand function (difficulty making a fist and difficulty holding objects) and pain (muscle pain and joint tenderness) were frequently endorsed and commonly associated with moderate to severe impact on daily activities.
This study confirmed the importance for quality of life of core symptoms of SSc, such as pain, fatigue and limitations in hand function. It also identified areas with very little research, such as sleep problems, that appear to play important roles in daily functioning, and that merit more focused study.</description><identifier>ISSN: 1462-0324</identifier><identifier>EISSN: 1462-0332</identifier><identifier>DOI: 10.1093/rheumatology/keq310</identifier><identifier>PMID: 21149249</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Activities of Daily Living ; Adult ; Aged ; Arthralgia - epidemiology ; Biological and medical sciences ; Canada - epidemiology ; Comorbidity ; Disability Evaluation ; Diseases of the osteoarticular system ; Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes ; Fatigue - epidemiology ; Female ; Hand Joints - physiopathology ; Health Surveys ; Humans ; Male ; Medical sciences ; Middle Aged ; Nervous system (semeiology, syndromes) ; Neurology ; Prevalence ; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis ; Scleroderma, Systemic - epidemiology ; Scleroderma, Systemic - ethnology ; Severity of Illness Index ; Sleep Wake Disorders - epidemiology</subject><ispartof>Rheumatology (Oxford, England), 2011-04, Vol.50 (4), p.762-767</ispartof><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c379t-78681c051160e191cf3a59e7c66011c09b32b2765f45205b7e266f252cb770d73</citedby><cites>FETCH-LOGICAL-c379t-78681c051160e191cf3a59e7c66011c09b32b2765f45205b7e266f252cb770d73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24014764$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21149249$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>BASSEL, Marielle</creatorcontrib><creatorcontrib>HUDSON, Marie</creatorcontrib><creatorcontrib>TAILLEFER, Suzanne S</creatorcontrib><creatorcontrib>SCHIEIR, Orit</creatorcontrib><creatorcontrib>BARON, Murray</creatorcontrib><creatorcontrib>THOMBS, Brett D</creatorcontrib><title>Frequency and impact of symptoms experienced by patients with systemic sclerosis: results from a Canadian National Survey</title><title>Rheumatology (Oxford, England)</title><addtitle>Rheumatology (Oxford)</addtitle><description>Knowledge about the range of symptoms experienced by patients with SSc, and their impact on daily functioning is limited. The objective of the present study was to identify symptoms of SSc that patients rated as frequent and that highly impacted their ability to carry out daily activities.
A total of 464 persons with SSc responded to the Canadian Scleroderma Patient Survey of Health Concerns and Research Priorities, including questions regarding the frequency and impact of 69 SSc symptoms. Descriptive analyses were performed dichotomizing symptom frequencies as never or rarely vs sometimes, most of the time or always and symptom impact on daily activities as no or minimal impact vs moderate to severe impact.
The five highest rated symptoms in terms of frequency and moderate to severe impact on daily activities, respectively, were: fatigue (89 and 72%), RP (86 and 67%), hand stiffness (81 and 59%), joint pain (81 and 64%) and difficulty sleeping (76 and 59%). In addition to these symptoms, items related to decreased hand function (difficulty making a fist and difficulty holding objects) and pain (muscle pain and joint tenderness) were frequently endorsed and commonly associated with moderate to severe impact on daily activities.
This study confirmed the importance for quality of life of core symptoms of SSc, such as pain, fatigue and limitations in hand function. It also identified areas with very little research, such as sleep problems, that appear to play important roles in daily functioning, and that merit more focused study.</description><subject>Activities of Daily Living</subject><subject>Adult</subject><subject>Aged</subject><subject>Arthralgia - epidemiology</subject><subject>Biological and medical sciences</subject><subject>Canada - epidemiology</subject><subject>Comorbidity</subject><subject>Disability Evaluation</subject><subject>Diseases of the osteoarticular system</subject><subject>Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes</subject><subject>Fatigue - epidemiology</subject><subject>Female</subject><subject>Hand Joints - physiopathology</subject><subject>Health Surveys</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Prevalence</subject><subject>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</subject><subject>Scleroderma, Systemic - epidemiology</subject><subject>Scleroderma, Systemic - ethnology</subject><subject>Severity of Illness Index</subject><subject>Sleep Wake Disorders - epidemiology</subject><issn>1462-0324</issn><issn>1462-0332</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkEtP3TAQhS0E4lV-QaXKG9TVBT8SO-muuioPCcGi7TpynEkxjePgcSj59xjdC2U1M5rvjOYcQj5zdsZZLc_jPczepDCEP8v5X3iUnO2QQ14osWJSit33XhQH5AjxgTFWclntkwPBeVGLoj4ky0WExxlGu1AzdtT5ydhEQ09x8VMKHik8TxBdJqCj7UInk_KQkP5z6T5TmMA7S9EOEAM6_EYj4DxkoI_BU0PXZjSdMyO9zcowmoH-nOMTLJ_IXm8GhJNtPSa_L378Wl-tbu4ur9ffb1ZW6jqtdKUqbvPjXDHgNbe9NGUN2irFeF7UrRSt0Krsi1KwstUglOpFKWyrNeu0PCZfN3enGLJTTI13aGEYzAhhxqYqK1GJuiozKTekzU4wQt9M0XkTl4az5jXy5mPkzSbyrPqyvT-3Hrp3zVvGGTjdAgatGfpoRuvwP1cwXmhVyBeSu5AU</recordid><startdate>20110401</startdate><enddate>20110401</enddate><creator>BASSEL, Marielle</creator><creator>HUDSON, Marie</creator><creator>TAILLEFER, Suzanne S</creator><creator>SCHIEIR, Orit</creator><creator>BARON, Murray</creator><creator>THOMBS, Brett D</creator><general>Oxford University Press</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20110401</creationdate><title>Frequency and impact of symptoms experienced by patients with systemic sclerosis: results from a Canadian National Survey</title><author>BASSEL, Marielle ; HUDSON, Marie ; TAILLEFER, Suzanne S ; SCHIEIR, Orit ; BARON, Murray ; THOMBS, Brett D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c379t-78681c051160e191cf3a59e7c66011c09b32b2765f45205b7e266f252cb770d73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Activities of Daily Living</topic><topic>Adult</topic><topic>Aged</topic><topic>Arthralgia - epidemiology</topic><topic>Biological and medical sciences</topic><topic>Canada - epidemiology</topic><topic>Comorbidity</topic><topic>Disability Evaluation</topic><topic>Diseases of the osteoarticular system</topic><topic>Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes</topic><topic>Fatigue - epidemiology</topic><topic>Female</topic><topic>Hand Joints - physiopathology</topic><topic>Health Surveys</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurology</topic><topic>Prevalence</topic><topic>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</topic><topic>Scleroderma, Systemic - epidemiology</topic><topic>Scleroderma, Systemic - ethnology</topic><topic>Severity of Illness Index</topic><topic>Sleep Wake Disorders - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BASSEL, Marielle</creatorcontrib><creatorcontrib>HUDSON, Marie</creatorcontrib><creatorcontrib>TAILLEFER, Suzanne S</creatorcontrib><creatorcontrib>SCHIEIR, Orit</creatorcontrib><creatorcontrib>BARON, Murray</creatorcontrib><creatorcontrib>THOMBS, Brett D</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Rheumatology (Oxford, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BASSEL, Marielle</au><au>HUDSON, Marie</au><au>TAILLEFER, Suzanne S</au><au>SCHIEIR, Orit</au><au>BARON, Murray</au><au>THOMBS, Brett D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Frequency and impact of symptoms experienced by patients with systemic sclerosis: results from a Canadian National Survey</atitle><jtitle>Rheumatology (Oxford, England)</jtitle><addtitle>Rheumatology (Oxford)</addtitle><date>2011-04-01</date><risdate>2011</risdate><volume>50</volume><issue>4</issue><spage>762</spage><epage>767</epage><pages>762-767</pages><issn>1462-0324</issn><eissn>1462-0332</eissn><abstract>Knowledge about the range of symptoms experienced by patients with SSc, and their impact on daily functioning is limited. The objective of the present study was to identify symptoms of SSc that patients rated as frequent and that highly impacted their ability to carry out daily activities.
A total of 464 persons with SSc responded to the Canadian Scleroderma Patient Survey of Health Concerns and Research Priorities, including questions regarding the frequency and impact of 69 SSc symptoms. Descriptive analyses were performed dichotomizing symptom frequencies as never or rarely vs sometimes, most of the time or always and symptom impact on daily activities as no or minimal impact vs moderate to severe impact.
The five highest rated symptoms in terms of frequency and moderate to severe impact on daily activities, respectively, were: fatigue (89 and 72%), RP (86 and 67%), hand stiffness (81 and 59%), joint pain (81 and 64%) and difficulty sleeping (76 and 59%). In addition to these symptoms, items related to decreased hand function (difficulty making a fist and difficulty holding objects) and pain (muscle pain and joint tenderness) were frequently endorsed and commonly associated with moderate to severe impact on daily activities.
This study confirmed the importance for quality of life of core symptoms of SSc, such as pain, fatigue and limitations in hand function. It also identified areas with very little research, such as sleep problems, that appear to play important roles in daily functioning, and that merit more focused study.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>21149249</pmid><doi>10.1093/rheumatology/keq310</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1462-0324 |
| ispartof | Rheumatology (Oxford, England), 2011-04, Vol.50 (4), p.762-767 |
| issn | 1462-0324 1462-0332 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_858282985 |
| source | MEDLINE; Oxford Journals - Connect here FIRST to enable access; Alma/SFX Local Collection |
| subjects | Activities of Daily Living Adult Aged Arthralgia - epidemiology Biological and medical sciences Canada - epidemiology Comorbidity Disability Evaluation Diseases of the osteoarticular system Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes Fatigue - epidemiology Female Hand Joints - physiopathology Health Surveys Humans Male Medical sciences Middle Aged Nervous system (semeiology, syndromes) Neurology Prevalence Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Scleroderma, Systemic - epidemiology Scleroderma, Systemic - ethnology Severity of Illness Index Sleep Wake Disorders - epidemiology |
| title | Frequency and impact of symptoms experienced by patients with systemic sclerosis: results from a Canadian National Survey |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-14T15%3A17%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Frequency%20and%20impact%20of%20symptoms%20experienced%20by%20patients%20with%20systemic%20sclerosis:%20results%20from%20a%20Canadian%20National%20Survey&rft.jtitle=Rheumatology%20(Oxford,%20England)&rft.au=BASSEL,%20Marielle&rft.date=2011-04-01&rft.volume=50&rft.issue=4&rft.spage=762&rft.epage=767&rft.pages=762-767&rft.issn=1462-0324&rft.eissn=1462-0332&rft_id=info:doi/10.1093/rheumatology/keq310&rft_dat=%3Cproquest_cross%3E858282985%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=858282985&rft_id=info:pmid/21149249&rfr_iscdi=true |