Suitability of chemiluminescent enzyme immunoassay for the measurement of blood tacrolimus concentrations in rheumatoid arthritis

The aim of this study was to evaluate the suitability of chemiluminescent enzyme immunoassay (CLIA) for the monitoring of whole-blood tacrolimus concentrations in rheumatoid arthritis (RA) patients. Sixty-three RA patients and 47 renal transplant (RT) patients treated with tacrolimus were enrolled....

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Veröffentlicht in:	Clinical biochemistry 2011-04, Vol.44 (5), p.397-402
Hauptverfasser:	Hirano, Kumi, Maruyama, Shuji, Mino, Yasuaki, Naito, Takafumi, Kawakami, Junichi
Format:	Artikel
Sprache:	eng
Schlagworte:	13- O-Demethylated tacrolimus 31- O-Demethylated tacrolimus ARCHITECT Arthritis, Rheumatoid - blood Biological and medical sciences Chromatography, High Pressure Liquid CLIA Cross-reactivity Diseases of the osteoarticular system HPLC-MS/MS Humans Immunoenzyme Techniques - methods Immunosuppressive Agents - blood Inflammatory joint diseases Investigative techniques, diagnostic techniques (general aspects) Luminescence Medical sciences Overestimation Renal transplantation Reproducibility of Results Rheumatoid arthritis Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the urinary system Tacrolimus Tacrolimus - blood Tandem Mass Spectrometry
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