Radiosynthesis and Biological Evaluation of l- and d-S-(3-[18F]Fluoropropyl)homocysteine for Tumor Imaging Using Positron Emission Tomography

Interest in radiolabeled amino acids for metabolic imaging of cancer and limitations with [11C]methionine has prompted the development of a new 18F-labeled methionine derivative S-(3-[18F]fluoropropyl)homocysteine ([18F]FPHCys). The l and d enantiomers of [18F]FPHCys were prepared from their respect...

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Veröffentlicht in:Journal of medicinal chemistry 2011-03, Vol.54 (6), p.1860-1870
Hauptverfasser: Bourdier, Thomas, Shepherd, Rachael, Berghofer, Paula, Jackson, Timothy, Fookes, Christopher J. R, Denoyer, Delphine, Dorow, Donna S, Greguric, Ivan, Gregoire, Marie-Claude, Hicks, Rodney J, Katsifis, Andrew
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Sprache:eng
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