Toward a practical and waste-free synthesis of thioureas in water

An operationally simple and entirely green protocol for the synthesis of thiourea derivatives by the reaction of carbon disulfide with primary amines in pure water is developed. This reaction is a highly atom-economic process for production of highly pure, hindered thioureas without any catalyst and...

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Veröffentlicht in:Molecular diversity 2011-02, Vol.15 (1), p.157-161
Hauptverfasser: Azizi, Najmedin, Khajeh-Amiri, Alireza, Ghafuri, Hossein, Bolourtchian, Mohammad
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container_issue 1
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container_title Molecular diversity
container_volume 15
creator Azizi, Najmedin
Khajeh-Amiri, Alireza
Ghafuri, Hossein
Bolourtchian, Mohammad
description An operationally simple and entirely green protocol for the synthesis of thiourea derivatives by the reaction of carbon disulfide with primary amines in pure water is developed. This reaction is a highly atom-economic process for production of highly pure, hindered thioureas without any catalyst and tedious work-up.
doi_str_mv 10.1007/s11030-010-9236-7
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source MEDLINE; SpringerLink Journals - AutoHoldings
subjects amines
Atom economy
Biochemistry
Biomedical and Life Sciences
Carbon
carbon disulfide
Chemical synthesis
Drug Discovery
Full-Length Paper
Green Chemistry Technology - methods
hydrochemistry
Life Sciences
Organic Chemistry
Pharmacy
Polymer Sciences
thiourea
Thiourea - chemical synthesis
Waste-free
Water
Water - chemistry
title Toward a practical and waste-free synthesis of thioureas in water
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