Toward a practical and waste-free synthesis of thioureas in water
An operationally simple and entirely green protocol for the synthesis of thiourea derivatives by the reaction of carbon disulfide with primary amines in pure water is developed. This reaction is a highly atom-economic process for production of highly pure, hindered thioureas without any catalyst and...
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Veröffentlicht in: | Molecular diversity 2011-02, Vol.15 (1), p.157-161 |
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container_title | Molecular diversity |
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creator | Azizi, Najmedin Khajeh-Amiri, Alireza Ghafuri, Hossein Bolourtchian, Mohammad |
description | An operationally simple and entirely green protocol for the synthesis of thiourea derivatives by the reaction of carbon disulfide with primary amines in pure water is developed. This reaction is a highly atom-economic process for production of highly pure, hindered thioureas without any catalyst and tedious work-up. |
doi_str_mv | 10.1007/s11030-010-9236-7 |
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subjects | amines Atom economy Biochemistry Biomedical and Life Sciences Carbon carbon disulfide Chemical synthesis Drug Discovery Full-Length Paper Green Chemistry Technology - methods hydrochemistry Life Sciences Organic Chemistry Pharmacy Polymer Sciences thiourea Thiourea - chemical synthesis Waste-free Water Water - chemistry |
title | Toward a practical and waste-free synthesis of thioureas in water |
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