Abuse and clinical value of diuretics in eating disorders therapeutic applications
OBJECTIVE: Diuretic abuse as a means of purging is common in patients with bulimia nervosa. We sought to illustrate the pathophysiologic effects of diuretics and purging on a patient with bulimia nervosa's fluid and electrolyte status and to clarify the role of diuretics in the management of vo...
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| Veröffentlicht in: | The International journal of eating disorders 2011-04, Vol.44 (3), p.200-202 |
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| container_title | The International journal of eating disorders |
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| creator | Mascolo, Margherita Chu, Eugene S Mehler, Philip S |
| description | OBJECTIVE: Diuretic abuse as a means of purging is common in patients with bulimia nervosa. We sought to illustrate the pathophysiologic effects of diuretics and purging on a patient with bulimia nervosa's fluid and electrolyte status and to clarify the role of diuretics in the management of volume status during refeeding. METHOD: We reviewed the literature pertaining to diuretic abuse, purging, bulimia nervosa, and diuretic therapy. RESULTS: Purging behaviors lead to volume depletion and a state of heightened aldosterone production. Patients with bulimia nervosa commonly undergo rapid rehydration with intravenous fluid administration. In the setting of hyperaldostreronism, aggressive rehydration leads to avid salt retention and the development of marked amounts of edema. DISCUSSION: Providers should understand both the background renal pathophysiology of the patient with bulimia nervosa and the mechanisms of action of diuretics to correctly use diuretics as focused therapeutic agents for this patient population. © 2010 by Wiley Periodicals, Inc. (Int J Eat Disord 2011; 44:200-202) |
| doi_str_mv | 10.1002/eat.20814 |
| format | Article |
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We sought to illustrate the pathophysiologic effects of diuretics and purging on a patient with bulimia nervosa's fluid and electrolyte status and to clarify the role of diuretics in the management of volume status during refeeding. METHOD: We reviewed the literature pertaining to diuretic abuse, purging, bulimia nervosa, and diuretic therapy. RESULTS: Purging behaviors lead to volume depletion and a state of heightened aldosterone production. Patients with bulimia nervosa commonly undergo rapid rehydration with intravenous fluid administration. In the setting of hyperaldostreronism, aggressive rehydration leads to avid salt retention and the development of marked amounts of edema. DISCUSSION: Providers should understand both the background renal pathophysiology of the patient with bulimia nervosa and the mechanisms of action of diuretics to correctly use diuretics as focused therapeutic agents for this patient population. © 2010 by Wiley Periodicals, Inc. (Int J Eat Disord 2011; 44:200-202)</description><identifier>ISSN: 0276-3478</identifier><identifier>EISSN: 1098-108X</identifier><identifier>DOI: 10.1002/eat.20814</identifier><identifier>PMID: 20186716</identifier><identifier>CODEN: INDIDJ</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adult and adolescent clinical studies ; Biological and medical sciences ; Bulimia ; bulimia nervosa ; Dehydration ; Diuretics ; Diuretics - adverse effects ; Drug abuse ; Drug therapy ; Eating behavior disorders ; Eating disorders ; Feeding and Eating Disorders - complications ; Feeding and Eating Disorders - physiopathology ; Feeding and Eating Disorders - psychology ; Humans ; Hyperaldosteronism - chemically induced ; Medical sciences ; pseudo-Bartter ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Substance-Related Disorders - complications ; Substance-Related Disorders - physiopathology ; Substance-Related Disorders - psychology ; Water-Electrolyte Balance</subject><ispartof>The International journal of eating disorders, 2011-04, Vol.44 (3), p.200-202</ispartof><rights>Copyright © 2010 Wiley Periodicals, Inc.</rights><rights>2015 INIST-CNRS</rights><rights>Copyright Wiley Periodicals Inc. 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J. Eat. Disord</addtitle><description>OBJECTIVE: Diuretic abuse as a means of purging is common in patients with bulimia nervosa. We sought to illustrate the pathophysiologic effects of diuretics and purging on a patient with bulimia nervosa's fluid and electrolyte status and to clarify the role of diuretics in the management of volume status during refeeding. METHOD: We reviewed the literature pertaining to diuretic abuse, purging, bulimia nervosa, and diuretic therapy. RESULTS: Purging behaviors lead to volume depletion and a state of heightened aldosterone production. Patients with bulimia nervosa commonly undergo rapid rehydration with intravenous fluid administration. In the setting of hyperaldostreronism, aggressive rehydration leads to avid salt retention and the development of marked amounts of edema. DISCUSSION: Providers should understand both the background renal pathophysiology of the patient with bulimia nervosa and the mechanisms of action of diuretics to correctly use diuretics as focused therapeutic agents for this patient population. © 2010 by Wiley Periodicals, Inc. (Int J Eat Disord 2011; 44:200-202)</description><subject>Adult and adolescent clinical studies</subject><subject>Biological and medical sciences</subject><subject>Bulimia</subject><subject>bulimia nervosa</subject><subject>Dehydration</subject><subject>Diuretics</subject><subject>Diuretics - adverse effects</subject><subject>Drug abuse</subject><subject>Drug therapy</subject><subject>Eating behavior disorders</subject><subject>Eating disorders</subject><subject>Feeding and Eating Disorders - complications</subject><subject>Feeding and Eating Disorders - physiopathology</subject><subject>Feeding and Eating Disorders - psychology</subject><subject>Humans</subject><subject>Hyperaldosteronism - chemically induced</subject><subject>Medical sciences</subject><subject>pseudo-Bartter</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Substance-Related Disorders - complications</subject><subject>Substance-Related Disorders - physiopathology</subject><subject>Substance-Related Disorders - psychology</subject><subject>Water-Electrolyte Balance</subject><issn>0276-3478</issn><issn>1098-108X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10F1r1jAUB_Agins2vfALaBFEvOh20rxfPo65CWOi29C7cJqmM7NPW5N2um9vtM8mCF6EA-F3XvgT8ozCPgWoDjxO-xVoyh-QFQWjSwr6y0OygkrJknGld8huStcAIBmIx2SnAqqlonJFPq3rOfkC-6ZwXeiDw664wW72xdAWTZijn4JLReiLvCT0V_kvDbHxMRXTVx9x9HMGBY5jl3unMPTpCXnUYpf8023dI5fvji4OT8rTD8fvD9enpeOc8bJFpR1y2RhZY12Dq4xDg7KqXZMf6pqjYFBrFC3jIJjyDXCjBTZGUc3ZHnm9zB3j8H32abKbkJzvOuz9MCerhaKMSkazfPmPvB7m2OfjMtJSmDw3ozcLcnFIKfrWjjFsMN5aCvZ3zDYnYP_EnO3z7cC53vjmXt7lmsGrLcCUI20j9i6kv45DBVzq7A4W9yN0_vb_G-3R-uJudbl0hDT5n_cdGL9ZqZgS9vPZsf1o1PnZyVtpRfYvFt_iYPEq5isuz_OdDKgRlWCG_QLfS6vB</recordid><startdate>201104</startdate><enddate>201104</enddate><creator>Mascolo, Margherita</creator><creator>Chu, Eugene S</creator><creator>Mehler, Philip S</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley</general><general>Wiley Subscription Services, Inc</general><scope>FBQ</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201104</creationdate><title>Abuse and clinical value of diuretics in eating disorders therapeutic applications</title><author>Mascolo, Margherita ; Chu, Eugene S ; Mehler, Philip S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4434-fa78ca46d96babb0c29ca9a62bcd2bca8b4a530b8a5f340537ed04985ad971843</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adult and adolescent clinical studies</topic><topic>Biological and medical sciences</topic><topic>Bulimia</topic><topic>bulimia nervosa</topic><topic>Dehydration</topic><topic>Diuretics</topic><topic>Diuretics - adverse effects</topic><topic>Drug abuse</topic><topic>Drug therapy</topic><topic>Eating behavior disorders</topic><topic>Eating disorders</topic><topic>Feeding and Eating Disorders - complications</topic><topic>Feeding and Eating Disorders - physiopathology</topic><topic>Feeding and Eating Disorders - psychology</topic><topic>Humans</topic><topic>Hyperaldosteronism - chemically induced</topic><topic>Medical sciences</topic><topic>pseudo-Bartter</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Substance-Related Disorders - complications</topic><topic>Substance-Related Disorders - physiopathology</topic><topic>Substance-Related Disorders - psychology</topic><topic>Water-Electrolyte Balance</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mascolo, Margherita</creatorcontrib><creatorcontrib>Chu, Eugene S</creatorcontrib><creatorcontrib>Mehler, Philip S</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>The International journal of eating disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mascolo, Margherita</au><au>Chu, Eugene S</au><au>Mehler, Philip S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Abuse and clinical value of diuretics in eating disorders therapeutic applications</atitle><jtitle>The International journal of eating disorders</jtitle><addtitle>Int. 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In the setting of hyperaldostreronism, aggressive rehydration leads to avid salt retention and the development of marked amounts of edema. DISCUSSION: Providers should understand both the background renal pathophysiology of the patient with bulimia nervosa and the mechanisms of action of diuretics to correctly use diuretics as focused therapeutic agents for this patient population. © 2010 by Wiley Periodicals, Inc. (Int J Eat Disord 2011; 44:200-202)</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>20186716</pmid><doi>10.1002/eat.20814</doi><tpages>3</tpages></addata></record> |
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| subjects | Adult and adolescent clinical studies Biological and medical sciences Bulimia bulimia nervosa Dehydration Diuretics Diuretics - adverse effects Drug abuse Drug therapy Eating behavior disorders Eating disorders Feeding and Eating Disorders - complications Feeding and Eating Disorders - physiopathology Feeding and Eating Disorders - psychology Humans Hyperaldosteronism - chemically induced Medical sciences pseudo-Bartter Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Substance-Related Disorders - complications Substance-Related Disorders - physiopathology Substance-Related Disorders - psychology Water-Electrolyte Balance |
| title | Abuse and clinical value of diuretics in eating disorders therapeutic applications |
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