Differential gene expression analysis identifies murine Cacnb3 as strongly upregulated in distinct dendritic cell populations upon stimulation

Langerhans cells (LCs) represent the dendritic cell (DC) population in the epidermis. Among the set of genes induced in primary mouse LCs in response to stimulation, both isoforms of the voltage-dependent Ca 2+ channel (VDCC) regulatory subunit Cacnb3 as well as the DC maturation marker Fscn1 were u...

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Veröffentlicht in:	Gene 2011-02, Vol.472 (1), p.18-27
Hauptverfasser:	Bros, Matthias, Dexheimer, Nadine, Ross, Ralf, Trojandt, Stefanie, Höhn, Yvette, Tampe, Jens, Sutter, Arne, Jährling, Frank, Grabbe, Stephan, Reske-Kunz, Angelika B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antigens Base Sequence Cacnb3 calcium Calcium channel Calcium Channels - genetics Calcium Channels - metabolism Cell Differentiation - genetics Dendritic cells Dendritic Cells - cytology Dendritic Cells - metabolism Fscn1 Gene Expression Regulation genes Langerhans cells Langerhans Cells - metabolism macrophages Mice Mice, Inbred BALB C mitogen-activated protein kinase Molecular Sequence Data promoter regions Protein Isoforms - genetics RNA, Messenger - metabolism Transfection Up-Regulation
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