Galectin-1 Enhances Astrocytic BDNF Production and Improves Functional Outcome in Rats Following Ischemia

Galectin-1, an endogenous mammalian lectin, has been implicated in a variety of CNS disorders. However, its role in cerebral ischemia is still elusive. In the present study, we investigated the effect of recombinant galectin-1 on production of astrocytic brain-derived neurotrophic factor (BDNF) and...

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Veröffentlicht in:	Neurochemical research 2010-11, Vol.35 (11), p.1716-1724
Hauptverfasser:	Qu, Wen-sheng, Wang, Yi-hui, Wang, Jian-ping, Tang, Ying-xin, Zhang, Qiang, Tian, Dai-shi, Yu, Zhi-yuan, Xie, Min-jie, Wang, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocytes - drug effects Astrocytes - metabolism Biochemistry Biomedical and Life Sciences Biomedicine Brain Ischemia - physiopathology Brain-Derived Neurotrophic Factor - biosynthesis Cell Biology Galectin 1 - pharmacology Galectin 1 - physiology Male Mice Neurochemistry Neurology Neurosciences Original Paper Rats Rats, Wistar Up-Regulation
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