Hypothalamic serotonin-1A receptor binding measured by PET predicts the plasma level of dehydroepiandrosterone sulfate in healthy women

Serotonin modulates the activity of the hypothalamic–pituitary–adrenal (HPA) axis particularly via the serotonin-1A receptor (5-HT 1A). Therefore, the rationale of this positron emission tomography (PET) study was to investigate the influence of the 5-HT 1A receptor distribution in the human brain o...

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Veröffentlicht in:	Neuroscience letters 2010-06, Vol.476 (3), p.161-165
Hauptverfasser:	Moser, Ulrike, Wadsak, Wolfgang, Spindelegger, Christoph, Mitterhauser, Markus, Mien, Leonhard-Key, Bieglmayer, Christian, Kletter, Kurt, Kasper, Siegfried, Lanzenberger, Rupert
Format:	Artikel
Sprache:	eng
Schlagworte:	5-HT 1A receptor Adult Biological and medical sciences Carbon Radioisotopes Dehydroepiandrosterone Sulfate - blood DHEAS Female Fundamental and applied biological sciences. Psychology HPA axis Humans Hydrocortisone - blood Hypothalamus Hypothalamus - diagnostic imaging Hypothalamus - metabolism PET Piperazines - metabolism Positron-Emission Tomography Predictive Value of Tests Pyridines - metabolism Radiopharmaceuticals - metabolism Receptor, Serotonin, 5-HT1A - metabolism Vertebrates: nervous system and sense organs Young Adult
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