p75 super(NTR) Mediates Ephrin-A Reverse Signaling Required for Axon Repulsion and Mapping

Reverse signaling by ephrin-As upon binding EphAs controls axon guidance and mapping. Ephrin-As are GPI-anchored to the membrane, requiring that they complex with transmembrane proteins that transduce their signals. We show that the p75 neurotrophin receptor (NTR) serves this role in retinal axons....

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Veröffentlicht in:Neuron (Cambridge, Mass.) Mass.), 2008-09, Vol.59 (5), p.746-758
Hauptverfasser: Lim, Yoo-Shick, McLaughlin, Todd, Sung, Tsung-Chang, Santiago, Alicia, Lee, Kuo-Fen, O'Leary, Dennis DM
Format: Artikel
Sprache:eng
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