Association analysis of GRIN1 and GRIN2B polymorphisms and Parkinson's disease in a hospital-based case–control study

Hyperactivation of N-methyl- d-aspartate receptors (NMDARs) leads to neuronal excitotoxicity and is suggested to play a role in many brain disorders, including Alzheimer's disease and schizophrenia. However, the association between polymorphisms in the genes that code for NMDAR subunits, N-meth...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience letters 2010-07, Vol.478 (2), p.61-65
Hauptverfasser:	Wu, Shey-Lin, Wang, Wen-Fu, Shyu, Hann-Yeh, Ho, Ying-Jui, Shieh, Jia-Ching, Fu, Yi-Ping, Wu, Shwu-Tzy, Cheng, Chun-Wen
Format:	Artikel
Sprache:	eng
Schlagworte:	Asian Continental Ancestry Group Biological and medical sciences Carrier Proteins - genetics Case-Control Studies Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Fundamental and applied biological sciences. Psychology Genetic Association Studies Genetic Markers Genetic Predisposition to Disease GRIN1 GRIN2B Hospitals Humans Medical sciences Nerve Tissue Proteins - genetics Neurology NMDAR Parkinson Disease - genetics Parkinson's disease Polymorphism, Single Nucleotide Receptors, N-Methyl-D-Aspartate - genetics Risk Assessment Single nucleotide polymorphism Taiwan Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!