Desirable properties of β₃-adrenoceptor agonists: Implications for the selection of drug development candidates

β₃-adrenoceptor agonists are currently in clinical development for the treatment of overactive bladder and considered for several other indications. This Perspective discusses desirable properties of such drugs mainly based on the example of overactive bladder, but at least partly they should also b...

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Veröffentlicht in:	European journal of pharmacology 2011-04, Vol.657 (1-3), p.1-3
Hauptverfasser:	Michel, Martin C, Cernecka, Hana, Ochodnicky, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-3 Receptor Agonists - metabolism Adrenergic beta-3 Receptor Agonists - pharmacokinetics Adrenergic beta-3 Receptor Agonists - pharmacology Adrenergic beta-3 Receptor Agonists - therapeutic use agonists Animals Biological and medical sciences bladder Drug Discovery - methods drugs genes Humans Ligands Medical sciences Nephrology. Urinary tract diseases pharmacokinetics Pharmacology. Drug treatments Polymorphism, Genetic Receptors, Adrenergic, beta-3 - genetics Receptors, Adrenergic, beta-3 - metabolism Risk screening Urinary system involvement in other diseases. Miscellaneous Urinary tract. Prostate gland
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