Vax2 regulates retinoic acid distribution and cone opsin expression in the vertebrate eye

Vax2 is an eye-specific homeobox gene, the inactivation of which in mouse leads to alterations in the establishment of a proper dorsoventral eye axis during embryonic development. To dissect the molecular pathways in which Vax2 is involved, we performed a transcriptome analysis of Vax2(-/-) mice thr...

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Veröffentlicht in:	Development (Cambridge) 2011-01, Vol.138 (2), p.261-271
Hauptverfasser:	Alfano, Giovanna, Conte, Ivan, Caramico, Tiziana, Avellino, Raffaella, Arnò, Benedetta, Pizzo, Maria Teresa, Tanimoto, Naoyuki, Beck, Susanne C, Huber, Gesine, Dollé, Pascal, Seeliger, Mathias W, Banfi, Sandro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified Cytochrome P-450 Enzyme System - genetics Cytochrome P-450 Enzyme System - metabolism Cytochrome P450 Family 26 Eye - growth & development Eye - metabolism Female Gene Expression Profiling Gene Expression Regulation, Developmental Homeodomain Proteins - genetics Homeodomain Proteins - metabolism In Situ Hybridization Male Mice Mice, Knockout Mice, Transgenic Opsins - genetics Opsins - metabolism Oryzias - genetics Oryzias - growth & development Oryzias - metabolism Oryzias latipes Pregnancy Retinal Cone Photoreceptor Cells - metabolism Retinoic Acid 4-Hydroxylase Rod Opsins - genetics Rod Opsins - metabolism Tretinoin - metabolism
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