A role for CD95 ligand in preventing graft rejection

TESTIS is a remarkable immune-privileged site, long known for its ability to support allogeneic and xenogeneic tissue transplants 1á¤-4 . Here we have investigated the molecular basis for testis immune privilege. Testis grafts derived from mice that can express functional CD95 (Fas or Apo-1) ligand...

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Veröffentlicht in:	Nature (London) 1995-10, Vol.377 (6550), p.630-632
Hauptverfasser:	Bellgrau, Donald, Gold, Daniel, Selawry, Helena, Moore, Jodene, Franzusoff, Alex, Duke, Richard C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Base Sequence DNA Primers Fas Ligand Protein fas Receptor - immunology Graft Rejection - immunology Graft Rejection - prevention & control Humanities and Social Sciences Immunity (Disease) Kidney - immunology Kidney - surgery Kidneys letter Male Membrane Glycoproteins - biosynthesis Membrane Glycoproteins - genetics Membrane Glycoproteins - immunology Mice Mice, Inbred BALB C Molecular biology Molecular Sequence Data multidisciplinary RNA, Messenger - metabolism Rodents Science Science (multidisciplinary) Sertoli Cells - immunology Sertoli Cells - metabolism Sertoli Cells - transplantation Testis - cytology Testis - immunology Testis - metabolism Tissue Transplantation Transplants & implants
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