Donor-specific antibody detection: comparison of single antigen assay and Luminex crossmatches

Luminex bead‐based assays are routinely used in the study of anti‐human leukocyte antigen (HLA) donor‐specific antibodies (DSA). Single antigen (SA) assays use beads coated with recombinant antigens whereas Luminex crossmatch (Xm‐DSA) tests consist of beads coated with isolated donor‐specific HLA mo...

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Veröffentlicht in:	Tissue antigens 2010-11, Vol.76 (5), p.398-403
Hauptverfasser:	Caro-Oleas, J. L., González-Escribano, M. F., Toro-Llamas, S., Acevedo, M. J., Martinez-Bravo, M. J., Aguilera, I., Núñez-Roldán, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibody-Dependent Cell Cytotoxicity Complement System Proteins - metabolism Cytotoxicity Cytotoxicity Tests, Immunologic donor-specific antibodies Female Histocompatibility antigen HLA Histocompatibility testing Histocompatibility Testing - methods Histocompatibility Testing - statistics & numerical data HLA antibodies HLA-A Antigens - immunology HLA-B Antigens - immunology HLA-DQ Antigens - immunology HLA-DR Antigens - immunology Humans Isoantibodies - blood Leukocytes Luminex crossmatches Pregnancy sensitivity Sensitivity and Specificity single antigen assay Tissue Donors Transplantation Immunology
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