Neurotrophins are required for nerve growth during development

Although the requirement of neurotrophins for the prevention of cell death in the peripheral nervous system is well established, their physiological involvement in nerve growth is still unclear. To address this question, we generated a mouse that expresses the green fluorescent protein in post-mitot...

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Veröffentlicht in:	Nature neuroscience 2001-01, Vol.4 (1), p.29-37
Hauptverfasser:	Barde, Yves-Alain, Tucker, Kerry Lee, Meyer, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Genetics and Genomics Animals Antibodies Antibodies, Monoclonal - pharmacology Axons Axons - drug effects Axons - physiology Behavioral Sciences Biological Techniques Biomedical and Life Sciences Biomedicine Brain-derived neurotrophic factor Brain-Derived Neurotrophic Factor - pharmacology Cell Differentiation - drug effects Cell Division - drug effects Cloning Cytochrome c Group - pharmacology Drug Carriers Embryos Growth Limb Buds - embryology Limb Buds - growth & development Limb Buds - innervation Luminescent Proteins - biosynthesis Luminescent Proteins - genetics Mice Mice, Transgenic Motor Neurons - cytology Motor Neurons - drug effects Motor Neurons - metabolism Nerve Growth Factor - pharmacology Nerve Growth Factors - metabolism Nerve Growth Factors - pharmacology Nervous system Neurobiology Neurons Neurons, Afferent - cytology Neurons, Afferent - drug effects Neurons, Afferent - metabolism Neurosciences Neurotrophic functions Peripheral Nerves - drug effects Peripheral Nerves - embryology Peripheral Nerves - growth & development Physiological aspects Physiology Proteins Publishing Spinal Nerves
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