Preserving the Lifesaving Power of Antimicrobial Agents

Many medical advances that physicians and patients take for granted are endangered by increasing antibiotic resistance and a distressing decline in the antibiotic research and development pipeline. Antibiotic-resistant infections have been estimated to cost the US health care system more than $20 bi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:JAMA : the journal of the American Medical Association 2011-03, Vol.305 (10), p.1027-1028
1. Verfasser: Hughes, James M
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1028
container_issue 10
container_start_page 1027
container_title JAMA : the journal of the American Medical Association
container_volume 305
creator Hughes, James M
description Many medical advances that physicians and patients take for granted are endangered by increasing antibiotic resistance and a distressing decline in the antibiotic research and development pipeline. Antibiotic-resistant infections have been estimated to cost the US health care system more than $20 billion annually and result in more than 8 million additional days in the hospital. Drug resistance is both a public health and national security threat. Here, Hughes determines how to limit the emergence and spread of antimicrobial-resistant organisms.
doi_str_mv 10.1001/jama.2011.279
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_856408820</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><ama_id>645988</ama_id><sourcerecordid>856408820</sourcerecordid><originalsourceid>FETCH-LOGICAL-a337t-68048914abd7ab066fd88d5b2ec8ed7161e10bf4f93eb1ae418db9ecc885c61f3</originalsourceid><addsrcrecordid>eNpdkDtPwzAQgC0EoqUwMrCgiIUpxY4fuYxVxUuqRAeYLTu5lFR5FDsF8e9xaMvALafTfXe6-wi5ZHTKKGV3a9OYaUIZmyZpdkTGTHKIuczgmIwpzSBOBYgROfN-TUMwnp6SUcK44FLIMUmXDj26z6pdRf07RouqRG9-y2X3hS7qymjW9lVT5a6zlamj2Qrb3p-Tk9LUHi_2eULeHu5f50_x4uXxeT5bxIbztI8VUAEZE8YWqbFUqbIAKKRNMAcsUqYYMmpLUWYcLTMoGBQ2wzwHkLliJZ-Q293ejes-tuh73VQ-x7o2LXZbr0EqQQESGsibf-S627o2HBcgUFImHAIU76DwjfcOS71xVWPct2ZUDz714FMPPnXwGfjr_dKtbbD4ow8CA3C1A4axQ1eJ4B_4D04teFc</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>858655238</pqid></control><display><type>article</type><title>Preserving the Lifesaving Power of Antimicrobial Agents</title><source>MEDLINE</source><source>American Medical Association Journals</source><creator>Hughes, James M</creator><creatorcontrib>Hughes, James M</creatorcontrib><description>Many medical advances that physicians and patients take for granted are endangered by increasing antibiotic resistance and a distressing decline in the antibiotic research and development pipeline. Antibiotic-resistant infections have been estimated to cost the US health care system more than $20 billion annually and result in more than 8 million additional days in the hospital. Drug resistance is both a public health and national security threat. Here, Hughes determines how to limit the emergence and spread of antimicrobial-resistant organisms.</description><identifier>ISSN: 0098-7484</identifier><identifier>EISSN: 1538-3598</identifier><identifier>DOI: 10.1001/jama.2011.279</identifier><identifier>PMID: 21343545</identifier><identifier>CODEN: JAMAAP</identifier><language>eng</language><publisher>United States: American Medical Association</publisher><subject>Anti-Bacterial Agents - pharmacology ; Anti-Bacterial Agents - therapeutic use ; Antibiotics ; Antimicrobial agents ; Bacterial Infections - drug therapy ; Drug Approval ; Drug Discovery ; Drug Industry ; Drug resistance ; Drug Resistance, Bacterial ; Health care expenditures ; Humans ; Inappropriate Prescribing ; Infections ; International Cooperation ; Population Surveillance ; Practice Patterns, Physicians ; Public Health ; R&amp;D ; Research &amp; development ; United States ; United States Food and Drug Administration</subject><ispartof>JAMA : the journal of the American Medical Association, 2011-03, Vol.305 (10), p.1027-1028</ispartof><rights>Copyright American Medical Association Mar 9, 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a337t-68048914abd7ab066fd88d5b2ec8ed7161e10bf4f93eb1ae418db9ecc885c61f3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://jamanetwork.com/journals/jama/articlepdf/10.1001/jama.2011.279$$EPDF$$P50$$Gama$$H</linktopdf><linktohtml>$$Uhttps://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2011.279$$EHTML$$P50$$Gama$$H</linktohtml><link.rule.ids>64,314,776,780,3327,27901,27902,76232,76235</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21343545$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hughes, James M</creatorcontrib><title>Preserving the Lifesaving Power of Antimicrobial Agents</title><title>JAMA : the journal of the American Medical Association</title><addtitle>JAMA</addtitle><description>Many medical advances that physicians and patients take for granted are endangered by increasing antibiotic resistance and a distressing decline in the antibiotic research and development pipeline. Antibiotic-resistant infections have been estimated to cost the US health care system more than $20 billion annually and result in more than 8 million additional days in the hospital. Drug resistance is both a public health and national security threat. Here, Hughes determines how to limit the emergence and spread of antimicrobial-resistant organisms.</description><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antibiotics</subject><subject>Antimicrobial agents</subject><subject>Bacterial Infections - drug therapy</subject><subject>Drug Approval</subject><subject>Drug Discovery</subject><subject>Drug Industry</subject><subject>Drug resistance</subject><subject>Drug Resistance, Bacterial</subject><subject>Health care expenditures</subject><subject>Humans</subject><subject>Inappropriate Prescribing</subject><subject>Infections</subject><subject>International Cooperation</subject><subject>Population Surveillance</subject><subject>Practice Patterns, Physicians</subject><subject>Public Health</subject><subject>R&amp;D</subject><subject>Research &amp; development</subject><subject>United States</subject><subject>United States Food and Drug Administration</subject><issn>0098-7484</issn><issn>1538-3598</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkDtPwzAQgC0EoqUwMrCgiIUpxY4fuYxVxUuqRAeYLTu5lFR5FDsF8e9xaMvALafTfXe6-wi5ZHTKKGV3a9OYaUIZmyZpdkTGTHKIuczgmIwpzSBOBYgROfN-TUMwnp6SUcK44FLIMUmXDj26z6pdRf07RouqRG9-y2X3hS7qymjW9lVT5a6zlamj2Qrb3p-Tk9LUHi_2eULeHu5f50_x4uXxeT5bxIbztI8VUAEZE8YWqbFUqbIAKKRNMAcsUqYYMmpLUWYcLTMoGBQ2wzwHkLliJZ-Q293ejes-tuh73VQ-x7o2LXZbr0EqQQESGsibf-S627o2HBcgUFImHAIU76DwjfcOS71xVWPct2ZUDz714FMPPnXwGfjr_dKtbbD4ow8CA3C1A4axQ1eJ4B_4D04teFc</recordid><startdate>20110309</startdate><enddate>20110309</enddate><creator>Hughes, James M</creator><general>American Medical Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7QP</scope><scope>7TK</scope><scope>7TS</scope><scope>7U7</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>NAPCQ</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20110309</creationdate><title>Preserving the Lifesaving Power of Antimicrobial Agents</title><author>Hughes, James M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a337t-68048914abd7ab066fd88d5b2ec8ed7161e10bf4f93eb1ae418db9ecc885c61f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Anti-Bacterial Agents - pharmacology</topic><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Antibiotics</topic><topic>Antimicrobial agents</topic><topic>Bacterial Infections - drug therapy</topic><topic>Drug Approval</topic><topic>Drug Discovery</topic><topic>Drug Industry</topic><topic>Drug resistance</topic><topic>Drug Resistance, Bacterial</topic><topic>Health care expenditures</topic><topic>Humans</topic><topic>Inappropriate Prescribing</topic><topic>Infections</topic><topic>International Cooperation</topic><topic>Population Surveillance</topic><topic>Practice Patterns, Physicians</topic><topic>Public Health</topic><topic>R&amp;D</topic><topic>Research &amp; development</topic><topic>United States</topic><topic>United States Food and Drug Administration</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hughes, James M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Physical Education Index</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>JAMA : the journal of the American Medical Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hughes, James M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preserving the Lifesaving Power of Antimicrobial Agents</atitle><jtitle>JAMA : the journal of the American Medical Association</jtitle><addtitle>JAMA</addtitle><date>2011-03-09</date><risdate>2011</risdate><volume>305</volume><issue>10</issue><spage>1027</spage><epage>1028</epage><pages>1027-1028</pages><issn>0098-7484</issn><eissn>1538-3598</eissn><coden>JAMAAP</coden><abstract>Many medical advances that physicians and patients take for granted are endangered by increasing antibiotic resistance and a distressing decline in the antibiotic research and development pipeline. Antibiotic-resistant infections have been estimated to cost the US health care system more than $20 billion annually and result in more than 8 million additional days in the hospital. Drug resistance is both a public health and national security threat. Here, Hughes determines how to limit the emergence and spread of antimicrobial-resistant organisms.</abstract><cop>United States</cop><pub>American Medical Association</pub><pmid>21343545</pmid><doi>10.1001/jama.2011.279</doi><tpages>2</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0098-7484
ispartof JAMA : the journal of the American Medical Association, 2011-03, Vol.305 (10), p.1027-1028
issn 0098-7484
1538-3598
language eng
recordid cdi_proquest_miscellaneous_856408820
source MEDLINE; American Medical Association Journals
subjects Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
Antibiotics
Antimicrobial agents
Bacterial Infections - drug therapy
Drug Approval
Drug Discovery
Drug Industry
Drug resistance
Drug Resistance, Bacterial
Health care expenditures
Humans
Inappropriate Prescribing
Infections
International Cooperation
Population Surveillance
Practice Patterns, Physicians
Public Health
R&D
Research & development
United States
United States Food and Drug Administration
title Preserving the Lifesaving Power of Antimicrobial Agents
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T03%3A31%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Preserving%20the%20Lifesaving%20Power%20of%20Antimicrobial%20Agents&rft.jtitle=JAMA%20:%20the%20journal%20of%20the%20American%20Medical%20Association&rft.au=Hughes,%20James%20M&rft.date=2011-03-09&rft.volume=305&rft.issue=10&rft.spage=1027&rft.epage=1028&rft.pages=1027-1028&rft.issn=0098-7484&rft.eissn=1538-3598&rft.coden=JAMAAP&rft_id=info:doi/10.1001/jama.2011.279&rft_dat=%3Cproquest_cross%3E856408820%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=858655238&rft_id=info:pmid/21343545&rft_ama_id=645988&rfr_iscdi=true