Vaccine-Induced Allo-HLA―Reactive Memory T Cells in a Kidney Transplantation Candidate

Allo-human leukocyte antigen (HLA) reactivity by naturally acquired viral-specific memory T cells is common. However, the effect of successful vaccination on the alloreactive memory T-cell repertoire is unclear. We hypothesized that vaccination could specifically induce allo-HLA-reactive memory T ce...

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Veröffentlicht in:	Transplantation 2011-03, Vol.91 (6), p.645-651
Hauptverfasser:	D'ORSOGNA, Lloyd J. A, VAN BESOUW, Nicole M, ROELEN, Dave L, DOXIADIS, Ilias I. N, CLAAS, Frans H. J, VAN DER MEER-PRINS, Ellen M. W, VAN DER POL, Pieter, FRANKE-VAN DIJK, Marry, ZOET, Yvonne M, VAN DER SLIK, Arno, WEIMAR, Willem, VAN KOOTEN, Cees, MULDER, Arend
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blast CD8 antigen Chickenpox Vaccine - immunology Cross Reactions Cross-reactivity Cytokines Cytotoxicity Cytotoxicity, Immunologic Endothelial cells Epithelial cells Fundamental and applied biological sciences. Psychology Fundamental immunology gamma -Interferon Histocompatibility antigen HLA HLA Antigens - immunology Humans Immediate-Early Proteins - immunology Immunologic Memory Immunological memory Kidney transplantation Kidney Transplantation - immunology Leukocytes Lymphocytes B Lymphocytes T Male Medical sciences Memory cells Middle Aged Organ Specificity phytohemagglutinins Prevention and actions Public health. Hygiene Public health. Hygiene-occupational medicine Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the urinary system T-Lymphocytes - immunology Tissue, organ and graft immunology Trans-Activators - immunology umbilical vein Vaccination Vaccines Varicella Varicella-zoster virus Viral Envelope Proteins - immunology
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