Human Bone Marrow–Derived Clonal Mesenchymal Stem Cells Inhibit Inflammation and Reduce Acute Pancreatitis in Rats

Background & Aims Acute pancreatitis (AP) has a high mortality rate; repetitive AP induces chronic AP and pancreatic adenocarcinoma. Mesenchymal stem cells (MSCs) have immunoregulatory effects and reduce inflammation. We developed a protocol to isolate human bone marrow–derived clonal MSCs (hcMS...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2011-03, Vol.140 (3), p.998-1008.e4
Hauptverfasser:	Jung, Kyung Hee, Song, Sun U, Yi, Tacghee, Jeon, Myung–Shin, Hong, Sang–Won, Zheng, Hong–Mei, Lee, Hee–Seung, Choi, Myung–Joo, Lee, Don–Haeng, Hong, Soon–Sun
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Biomarkers - metabolism Bone Marrow Transplantation CD3 Complex - metabolism Cell Differentiation Cell Proliferation Cells, Cultured Ceruletide CM-DiI Coculture Techniques Cytokines - metabolism Disease Models, Animal Forkhead Transcription Factors - metabolism Gastroenterology and Hepatology Humans In Situ Hybridization, Fluorescence Inflammation Mediators - metabolism Inflammatory Disorders Mesenchymal Stem Cell Transplantation Pancreas - immunology Pancreas - metabolism Pancreas - pathology Pancreas - surgery Pancreatitis - chemically induced Pancreatitis - immunology Pancreatitis - metabolism Pancreatitis - pathology Pancreatitis - surgery Rats Rats, Sprague-Dawley Rats, Wistar Regeneration Severity of Illness Index Stem Cell Therapy T-Lymphocytes - immunology Taurocholic Acid TCA Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!