Urinary epidermal growth factor, monocyte chemotactic protein-1, and β2-microglobulin in children with ureteropelvic junction obstruction

We demonstrated down-regulation of epidermal growth factor (EGF) and up-regulation of monocyte chemotactic protein-1 (MCP-1) in the renal parenchyma in children who underwent pyeloplasty for ureteropelvic junction obstruction (UPJO). These findings were paralleled by urinary levels of EGF and MCP-1...

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Veröffentlicht in:	Journal of pediatric surgery 2011-03, Vol.46 (3), p.530-536
Hauptverfasser:	Bartoli, Fabio, Penza, Rosa, Aceto, Gabriella, Niglio, Francesco, D'Addato, Olinda, Pastore, Valentina, Campanella, Vittoria, Magaldi, Simona, Lasalandra, Carla, Di Bitonto, Giovanna, Gesualdo, Loreto
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent beta 2-Microglobulin - biosynthesis beta 2-Microglobulin - genetics beta 2-Microglobulin - urine Biomarkers Chemokine CCL2 - biosynthesis Chemokine CCL2 - genetics Chemokine CCL2 - urine Child Child, Preschool Children EGF Epidermal Growth Factor - biosynthesis Epidermal Growth Factor - genetics Epidermal Growth Factor - urine Female Gene Expression Regulation Humans Hydronephrosis Infant Infant, Newborn Kidney Pelvis - abnormalities Kidney Pelvis - surgery Kidney Tubules, Proximal - metabolism Male MCP-1 Postoperative Period Ureter - abnormalities Ureter - surgery Ureteral Obstruction - congenital Ureteral Obstruction - metabolism Ureteral Obstruction - surgery Ureteropelvic junction obstruction β2-Microglobulin
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