Performance of a vortex flow bioreactor for cultivation of CHO-K1 cells on microcarriers

In biochemical processes involving cultivation of animal cells, the design of a bioreactor is important because it should enable the provision of appropriate oxygen and nutrients to the culture medium at low shear stress. The aim of this study is to evaluate a new bioreactor designed and built based...

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Veröffentlicht in:	Process biochemistry (1991) 2011, Vol.46 (1), p.35-45
Hauptverfasser:	Santiago, Patrícia Aparecida, Giordano, Roberto de Campos, Suazo, Claudio Alberto Torres
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal cell culture biochemical pathways Bioreactor bioreactors cell culture cell viability Chinese hamsters culture media hydrodynamics mass transfer Microcarriers nutrients oxygen Oxygen transfer Shear stress Taylor vortex flow
Online-Zugang:	Volltext
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