Alterations in perivascular adipose tissue structure and function in hypertension

We studied the structural and the functional alterations of perivascular adipose tissue (PVAT) in hypertension with spontaneously hypertensive rats (SHR). Measured with dual energy X-ray absorptiometry, a smaller body fat mass and a greater lean mass were found in SHR than in Wistar–Kyoto (WKY) rats...

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Veröffentlicht in:	European journal of pharmacology 2011-04, Vol.656 (1-3), p.68-73
Hauptverfasser:	Lu, Chao, Su, Li-Ying, Lee, Robert M.K.W., Gao, Yu-Jing
Format:	Artikel
Sprache:	eng
Schlagworte:	adipocytes Adipocytes, Brown - metabolism Adipocytes, Brown - pathology adipose tissue Adipose Tissue - metabolism Adipose Tissue - pathology agonists Animals antagonists Aorta Arterial hypertension. Arterial hypotension bioassays Biological and medical sciences Blood and lymphatic vessels Blood Pressure Blood Vessels - pathology body fat Body Weight Brown adipocyte Cardiology. Vascular system Contraction dual-energy X-ray absorptiometry endothelium Endothelium, Vascular - metabolism Endothelium, Vascular - pathology Hypertension Hypertension - pathology Hypertension - physiopathology Male Medical sciences Perivascular adipose tissue pharmacology Pharmacology. Drug treatments phenylephrine Rats Spontaneously hypertensive rat Uncoupling protein-1 Vasoconstriction Vasodilation
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