Infliximab therapy in pediatric Takayasu’s arteritis: report of two cases
Takayasu arteritis (TA) is a chronic vasculitis of unknown etiology. Experience with anti-tumor necrosis factor alpha (anti-TNF) agents in difficult-to-treat patients with TA is limited and refers to adult patients. Here, we present two cases of pediatric TA treated with infliximab, in which clinica...
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| Veröffentlicht in: | Rheumatology international 2011, Vol.31 (1), p.93-95 |
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| container_end_page | 95 |
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| container_title | Rheumatology international |
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| creator | Buonuomo, Paola Sabrina Bracaglia, Claudia Campana, Andrea Insalaco, Antonella Pardeo, Manuela Cortis, Elisabetta Ugazio, Alberto G. |
| description | Takayasu arteritis (TA) is a chronic vasculitis of unknown etiology. Experience with anti-tumor necrosis factor alpha (anti-TNF) agents in difficult-to-treat patients with TA is limited and refers to adult patients. Here, we present two cases of pediatric TA treated with infliximab, in which clinical remission was observed. Anti-TNF treatment represents a useful therapy in pediatric Takayasu arteritis too, especially to avoid the risk of long-term corticosteroids toxicity. |
| doi_str_mv | 10.1007/s00296-009-1147-5 |
| format | Article |
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| language | eng |
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| source | MEDLINE; SpringerNature Journals |
| subjects | Adolescent Anti-Inflammatory Agents - therapeutic use Antibodies, Monoclonal - therapeutic use Case Report Female Humans Infliximab Medicine Medicine & Public Health Rheumatology Takayasu Arteritis - therapy Treatment Outcome Tumor Necrosis Factor-alpha - antagonists & inhibitors |
| title | Infliximab therapy in pediatric Takayasu’s arteritis: report of two cases |
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