Predictors of survival after gastrointestinal complications in bypass grafting
Between April 2001 and December 2005, data were collected prospectively from 2,320 consecutive patients who underwent first-time coronary artery bypass. Logistic multiple regression analyses were carried out to determine the independent predictors of gastrointestinal complications and death. There w...
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| Veröffentlicht in: | Asian cardiovascular & thoracic annals 2011-02, Vol.19 (1), p.27-32 |
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| creator | Vohra, Hunaid A Farid, Shakil Bahrami, Toufan Gaer, Jullien AR |
| description | Between April 2001 and December 2005, data were collected prospectively from 2,320 consecutive patients who underwent first-time coronary artery bypass. Logistic multiple regression analyses were carried out to determine the independent predictors of gastrointestinal complications and death. There were 65 major gastrointestinal complications identified in 65 (2.8%) patients: paralytic ileus in 15, mesenteric ischemia in 12, upper gastrointestinal hemorrhage in 16, lower gastrointestinal hemorrhage in 8, small bowel obstruction in 5, pseudoobstruction in 5, and others in 4. The 30-day mortality was 21.5% (14 patients). Female sex, preoperative creatinine >200 µmol·L−1, previous gastrointestinal pathology, low cardiac output, readmission to the intensive care unit, postoperative pulmonary complications, arrhythmias, hemofiltration, and reoperation were independent predictors of major gastrointestinal complications. Independent risk factors for death were readmission to the intensive care unit, the need for hemofiltration, reoperation, and ischemic bowel. Careful hemodynamic control and optimization of perioperative organ perfusion are important to minimize the mortality associated with major gastrointestinal complications after coronary artery bypass. |
| doi_str_mv | 10.1177/0218492310394803 |
| format | Article |
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Logistic multiple regression analyses were carried out to determine the independent predictors of gastrointestinal complications and death. There were 65 major gastrointestinal complications identified in 65 (2.8%) patients: paralytic ileus in 15, mesenteric ischemia in 12, upper gastrointestinal hemorrhage in 16, lower gastrointestinal hemorrhage in 8, small bowel obstruction in 5, pseudoobstruction in 5, and others in 4. The 30-day mortality was 21.5% (14 patients). Female sex, preoperative creatinine >200 µmol·L−1, previous gastrointestinal pathology, low cardiac output, readmission to the intensive care unit, postoperative pulmonary complications, arrhythmias, hemofiltration, and reoperation were independent predictors of major gastrointestinal complications. Independent risk factors for death were readmission to the intensive care unit, the need for hemofiltration, reoperation, and ischemic bowel. 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Logistic multiple regression analyses were carried out to determine the independent predictors of gastrointestinal complications and death. There were 65 major gastrointestinal complications identified in 65 (2.8%) patients: paralytic ileus in 15, mesenteric ischemia in 12, upper gastrointestinal hemorrhage in 16, lower gastrointestinal hemorrhage in 8, small bowel obstruction in 5, pseudoobstruction in 5, and others in 4. The 30-day mortality was 21.5% (14 patients). Female sex, preoperative creatinine >200 µmol·L−1, previous gastrointestinal pathology, low cardiac output, readmission to the intensive care unit, postoperative pulmonary complications, arrhythmias, hemofiltration, and reoperation were independent predictors of major gastrointestinal complications. Independent risk factors for death were readmission to the intensive care unit, the need for hemofiltration, reoperation, and ischemic bowel. Careful hemodynamic control and optimization of perioperative organ perfusion are important to minimize the mortality associated with major gastrointestinal complications after coronary artery bypass.</description><subject>Aged</subject><subject>Chi-Square Distribution</subject><subject>Coronary Artery Bypass - adverse effects</subject><subject>Coronary Artery Bypass - mortality</subject><subject>England - epidemiology</subject><subject>Female</subject><subject>Gastrointestinal Diseases - etiology</subject><subject>Gastrointestinal Diseases - mortality</subject><subject>Gastrointestinal Diseases - physiopathology</subject><subject>Hemodynamics</subject><subject>Humans</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Prospective Studies</subject><subject>Risk Assessment</subject><subject>Risk Factors</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>0218-4923</issn><issn>1816-5370</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kM1LxDAUxIMo7rp69yS9eaq-1yRNepTFL1jUg55LmqYlS9vUpF3Y_96WVQ-CpwdvfjMMQ8glwg2iELeQoGRZQhFoxiTQI7JEiWnMqYBjspzleNYX5CyELQBQpPKULBKkXFBkS_Ly5k1p9eB8iFwVhdHv7E41kaoG46NahcE72w0mDLab3tq1fWO1GqzrQmS7qNj3KoSo9pPBdvU5OalUE8zF912Rj4f79_VTvHl9fF7fbWKdcBziymCZcsnTCjKmDQemMKVoNAIaKRQ3QmPBKYisVFPrAgQviwxYYVLDREZX5PqQ23v3OU7t8tYGbZpGdcaNIZec8ZRROZNwILV3IXhT5b23rfL7HCGfR8z_jjhZrr7Dx6I15a_hZ7UJiA9AULXJt2700zbh_8AvdeZ5uw</recordid><startdate>201102</startdate><enddate>201102</enddate><creator>Vohra, Hunaid A</creator><creator>Farid, Shakil</creator><creator>Bahrami, Toufan</creator><creator>Gaer, Jullien AR</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201102</creationdate><title>Predictors of survival after gastrointestinal complications in bypass grafting</title><author>Vohra, Hunaid A ; Farid, Shakil ; Bahrami, Toufan ; Gaer, Jullien AR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c251t-fe1d65856f094ce504a1631ec101e87a5e7c1b53079da003b075db904be6e4793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Aged</topic><topic>Chi-Square Distribution</topic><topic>Coronary Artery Bypass - adverse effects</topic><topic>Coronary Artery Bypass - mortality</topic><topic>England - epidemiology</topic><topic>Female</topic><topic>Gastrointestinal Diseases - etiology</topic><topic>Gastrointestinal Diseases - mortality</topic><topic>Gastrointestinal Diseases - physiopathology</topic><topic>Hemodynamics</topic><topic>Humans</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Prospective Studies</topic><topic>Risk Assessment</topic><topic>Risk Factors</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><toplevel>online_resources</toplevel><creatorcontrib>Vohra, Hunaid A</creatorcontrib><creatorcontrib>Farid, Shakil</creatorcontrib><creatorcontrib>Bahrami, Toufan</creatorcontrib><creatorcontrib>Gaer, Jullien AR</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Asian cardiovascular & thoracic annals</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vohra, Hunaid A</au><au>Farid, Shakil</au><au>Bahrami, Toufan</au><au>Gaer, Jullien AR</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Predictors of survival after gastrointestinal complications in bypass grafting</atitle><jtitle>Asian cardiovascular & thoracic annals</jtitle><addtitle>Asian Cardiovasc Thorac Ann</addtitle><date>2011-02</date><risdate>2011</risdate><volume>19</volume><issue>1</issue><spage>27</spage><epage>32</epage><pages>27-32</pages><issn>0218-4923</issn><eissn>1816-5370</eissn><abstract>Between April 2001 and December 2005, data were collected prospectively from 2,320 consecutive patients who underwent first-time coronary artery bypass. Logistic multiple regression analyses were carried out to determine the independent predictors of gastrointestinal complications and death. There were 65 major gastrointestinal complications identified in 65 (2.8%) patients: paralytic ileus in 15, mesenteric ischemia in 12, upper gastrointestinal hemorrhage in 16, lower gastrointestinal hemorrhage in 8, small bowel obstruction in 5, pseudoobstruction in 5, and others in 4. The 30-day mortality was 21.5% (14 patients). Female sex, preoperative creatinine >200 µmol·L−1, previous gastrointestinal pathology, low cardiac output, readmission to the intensive care unit, postoperative pulmonary complications, arrhythmias, hemofiltration, and reoperation were independent predictors of major gastrointestinal complications. Independent risk factors for death were readmission to the intensive care unit, the need for hemofiltration, reoperation, and ischemic bowel. Careful hemodynamic control and optimization of perioperative organ perfusion are important to minimize the mortality associated with major gastrointestinal complications after coronary artery bypass.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>21357314</pmid><doi>10.1177/0218492310394803</doi><tpages>6</tpages></addata></record> |
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| subjects | Aged Chi-Square Distribution Coronary Artery Bypass - adverse effects Coronary Artery Bypass - mortality England - epidemiology Female Gastrointestinal Diseases - etiology Gastrointestinal Diseases - mortality Gastrointestinal Diseases - physiopathology Hemodynamics Humans Logistic Models Male Middle Aged Prospective Studies Risk Assessment Risk Factors Time Factors Treatment Outcome |
| title | Predictors of survival after gastrointestinal complications in bypass grafting |
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