Organ-specific dietary fatty acid uptake in humans using positron emission tomography coupled to computed tomography

A noninvasive method to determine postprandial fatty acid tissue partition may elucidate the link between excess dietary fat and type 2 diabetes. We hypothesized that the positron-emitting fatty acid analog 14(R,S)-[(18)F]fluoro-6-thia-heptadecanoic acid ((18)FTHA) administered orally during a meal...

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Veröffentlicht in:	American journal of physiology: endocrinology and metabolism 2011-03, Vol.300 (3), p.E445-E453
Hauptverfasser:	Labbé, Sébastien M, Grenier-Larouche, Thomas, Croteau, Etienne, Normand-Lauzière, François, Frisch, Frédérique, Ouellet, René, Guérin, Brigitte, Turcotte, Eric E, Carpentier, André C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Animals Blood Glucose - metabolism Chylomicrons - metabolism Diabetes Diabetes Mellitus, Type 2 - metabolism Dietary Fats - pharmacokinetics Fatty acids Fatty Acids - pharmacokinetics Fatty Acids, Nonesterified - blood Humans Insulin - blood Insulin Resistance - physiology Male Men Metabolism Middle Aged Oils & fats Palmitates - metabolism Positron-Emission Tomography Radiopharmaceuticals - pharmacokinetics Rats Rats, Wistar Rodents Tissues Tomography Tomography, Emission-Computed Toxicity Triazoles - pharmacokinetics Triglycerides - blood Triglycerides - metabolism Whole-Body Counting Young Adult
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