Synthesis and HIV-1 inhibitory activity of natural products isolated from Gnetum parvifolium and their analogues

Resveratrol, isorhapontigenin and pinosylvin, isolated from Gnetum parvifolium, and their analogues have been synthesized and tested for their inhibitory activity of HIV-1. Natural product 12a and analogues (12d, 12e, 12g) display significant inhibitory activity of HIV-1 replication. Among them, com...

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Veröffentlicht in:	Yao hsüeh hsüeh pao 2010-12, Vol.45 (12), p.1509-1515
Hauptverfasser:	Piao, Zhi-song, Feng, Ya-bing, Wang, Lin, Zhang, Xing-quan, Lin, Mao
Format:	Artikel
Sprache:	chi
Schlagworte:	Anti-HIV Agents - isolation & purification Anti-HIV Agents - pharmacology Cells, Cultured Drugs, Chinese Herbal - isolation & purification Drugs, Chinese Herbal - pharmacology Gnetum - chemistry HIV-1 - drug effects HIV-1 - physiology Inhibitory Concentration 50 Leukocytes, Mononuclear - cytology Leukocytes, Mononuclear - virology Molecular Structure Plants, Medicinal - chemistry Stilbenes - chemical synthesis Stilbenes - chemistry Stilbenes - isolation & purification Stilbenes - pharmacology Virus Replication - drug effects
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